Senior Software Engineer, Web

Knowtex.ai Senior Software Engineer, Web LOCATION San Francisco, CA (in office 3 days a week) EMPLOYMENT Full-time, individual contributor WORK AUTHORIZATION Must be authorized to work in the U.S.; we are unable to sponsor visas for this role

About Knowtex.ai Knowtex is the first frontier AI lab for healthcare that is building AI to save human lives. We built an AI system that executes the most complex workflows in medicine and empowers clinicians with clinical intelligence capabilities, so every patient can receive the best care possible.

Position Overview We are seeking a frontend-leaning engineer to help build and scale Clinical Intelligence capabilities in our user-facing web application. You will work closely with Platform Engineering and customer-facing teams to build accessible, intuitive, and performant user experiences that support real-time AI workflows across enterprise healthcare environments. This role is ideal for an engineer who has experience operating on small, high-impact teams with significant ownership and autonomy, including end-to-end execution on critical product features. Key Responsibilities

• Maintain and expand core Clinical Intelligence experiences, including AI assistants, patient context, patient search, trial and drug eligibility, and other emerging workflows

• Build and scale client-side EHR-integrated features

• Maintain complex audio-centric workflows

• Develop accessible, intuitive, and performant user interfaces

• Develop secure and performant APIs and supporting infrastructure for web and mobile applications

• Collaborate closely with engineering, product, and customer delivery teams to prioritize bug fixes, improvements, and new feature development

• Participate meaningfully in technical discussions, design reviews, and code reviews

• Improve system reliability, observability, and performance

• Handle engineering escalations from customer-facing teams, including investigating issues outside of your typical areas of responsibility

Required Qualifications

• 5+ years of experience building production web applications

• Strong proficiency in TypeScript

• Experience building applications with React and Node.js

• Experience designing and building RESTful APIs

• Experience working with relational and/or NoSQL databases

• Understanding of distributed systems and scalability concepts

• Strong debugging, communication, and problem-solving skills

• Significant experience using agentic coding tools to aid in the SDLC

Preferred Qualifications

• Experience in healthcare technology or regulated environments

• Experience building real-time or highly interactive web applications

• Familiarity with AWS services such as Lambda, ECS, S3, RDS, and DynamoDB

Technical Environment

• React, TypeScript, Node.js, and Python (Lambda)

• AWS cloud infrastructure (including GovCloud environments)

• AI-enabled application platforms

• CI/CD pipelines and containerized services

• Observability and analytics tools (Amplitude, Sentry)

Compensation & Benefits

• Meaningful equity compensation

• Unlimited PTO

• Premium health, dental, and vision coverage

• 401(k) plan

Why Knowtex? Mission that matters Our product sits inside real-time clinical care. Every workflow you improve gives a clinician time back and makes a patient's documentation safer and more complete. Already at scale You'll ship to a deployment spanning hundreds of VA sites and tens of thousands of clinicians, plus a growing commercial base — with impact backed by peer-reviewed research. AI-native ways of working We're a frontier AI lab for healthcare, and we work like one: AI tooling is part of how you prototype, analyze, and ship every day. Growth and training Onboarding on our product, clinical documentation workflows, and customer base; HIPAA and security/compliance training (plus VA/federal training where relevant); shadowing implementations and site visits; and direct mentorship from the CTO.

Knowtex is an equal opportunity employer committed to building a diverse team that reflects the clinicians and patients we serve.