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Structural Biologist III

Tempus

Aliso Viejo, CAFull-time$120–170K/yrPosted 2w agoStill listed 1 day ago

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At a glance

Compensation
$120–170K/yr
Location
Aliso Viejo, CA
Schedule
Full-time
Work Authorization
Not specified

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Requirements

Credentials this posting asks for.

Doctorate

Job overview

The Structural Biologist III collaborates across biology, bioinformatics, software engineering, and clinical teams to design tools and methodologies that leverage biomolecular structural data for guiding clinical decisions.

Skills & qualifications

RequiredNice to have

Skills

PythonRPerlC/C++JavaSQLBioinformatics SoftwareSystems BiologyMolecular DynamicsX‑RayCryo‑EM

Qualifications

PhD in Computational Biology or Equivalent5+ Years R&D Experience in Computational Structural Biology2+ Years Post‑Doctoral Experience2+ Years Management Experience

Full job description

Compensation: $120,000 - $170,000 Role Overview The Structural Biologist III collaborates across biology, bioinformatics, software engineering, and clinical teams to design tools and methodologies leveraging biomolecular structural data to guide clinical decisions.

Key Responsibilities

  • Provide structural biology support for variant analyses through structure-function relationship interpretation.

  • Develop novel methods, protocols, and tools for structural modeling, molecular dynamics, and clinical variant assessment on internal platforms.

  • Partner with statisticians and data scientists to validate algorithms and data collection workflows.

  • Coordinate cross-functional efforts across Bioinformatics, R&D, and reporting teams for clinical research projects.

  • Write testable, production-grade code adhering to SDLC standards and code review best practices.

  • Maintain technical documentation, SOPs, and knowledge bases while mentoring junior staff.

  • Direct and lead the structural team through both soft and explicit leadership ensuring timely project completion

  • Support, inform, and educate leadership and stakeholders about project progress and blockers.

Qualifications & Competencies

  • Education: PhD in computational biology, structural biology, biophysics, bioinformatics, or equivalent.

  • Experience: Minimum 5 years of R&D experience in computational structural biology or related fields, including at least 2 years of post-doctoral or industrial experience and 2 years management experience.

  • Technical Skills: Fluency/proficiency in scripting/languages (Python, R, Perl, C/C++, Java, SQL) and bioinformatics/modeling software. Strong background in systems biology, molecular dynamics, and experimental techniques (X-ray, Cryo-EM).

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