Associate Staff Scientist (Intestinal Organoids)

Join CuSTOM Accelerator at Cincinnati Children's Want to work alongside a multidisciplinary team of scientists, clinicians, surgeons, bioengineers, computational scientists, and entrepreneurs united by a common goal of accelerating discovery and translating organoid technologies from the laboratory to real-world applications? At the CuSTOM Accelerator, we work at the intersection of academia, industry, and clinical translation to develop next-generation human organoid platforms that advance disease modeling, drug discovery, predictive toxicology, precision medicine, and regenerative therapies. As we expand our efforts in intestinal biology, stem cell technologies, and organoid-based applications, we are seeking a highly motivated Associate Staff Scientist to play a key role in this next phase of growth. This is a unique opportunity to contribute to projects spanning the development of advanced human-relevant models of intestinal development, physiology, regeneration, and disease, including inflammatory bowel disease (IBD), the creation of predictive platforms for therapeutic discovery and safety assessment, and the advancement of stem cell-derived intestinal organoids for regenerative medicine applications. We offer a highly collaborative and innovative scientific environment with extensive opportunities for professional growth, scientific leadership, publication, and translational impact. There is no better place to make a meaningful contribution to medicine, patients, and society. What You Will Do The successful candidate will join a team focused on advancing and scaling human stem cell-derived intestinal organoid technologies and their applications in disease modeling, therapeutic development, and regenerative medicine. The overall goal of this program is to transform traditional approaches to biomedical research and drug development by creating more predictive, scalable, and reproducible human stem cell-based models. In this role, you will: * Lead the development, optimization, and characterization of induced pluripotent stem cell (iPSC)-derived intestinal organoid models for disease modeling, therapeutic discovery, regenerative medicine, and translational applications. * Establish and implement novel protocols for stem cell differentiation, organoid culture, maturation, and functional assessment. * Investigate mechanisms of intestinal development, epithelial regeneration, and tissue maturation using human stem cell-derived organoid systems. * Contribute to the development and preclinical evaluation of stem cell-derived intestinal tissues and regenerative medicine strategies aimed at restoring intestinal function. * Characterize organoid models using molecular, cellular, biochemical, imaging, and functional approaches. * Design, execute, analyze, and interpret experimental studies independently. * Collaborate closely with experts in developmental biology, bioengineering, automation, imaging, data science, surgery, and translational medicine to advance organoid platforms and workflows. * Contribute to the development of scalable and automated organoid manufacturing and screening technologies. * Present scientific findings at laboratory meetings, seminars, and national or international conferences. * Prepare manuscripts, abstracts, technical reports, grant applications, and other scientific communications. * Mentor and supervise junior scientists, trainees, and laboratory