Scientist I, Drug Metabolism and Pharmacokinetics

Description

Boehringer Ingelheim is seeking a highly motivated Scientist I to join the Drug Metabolism & Transport (DM&T) group at our US headquarters in Ridgefield, CT.

As a Scientist I, you will work closely with DM&T colleagues, conducting in vitro studies to evaluate the absorption, distribution, metabolism and excretion (ADME) of small molecule drug candidates. Studies will include the mechanistic interaction of drugs, metabolites, and selected reference compounds with drug metabolizing enzymes. Additionally, studies may include evaluating the distribution of investigational compounds into cells or tissues using advanced technology and radiolabeled materials.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development, and delivery of our products to our patients and customers. Our global presence provides an opportunity for all employees to collaborate internationally, offering visibility and the opportunity to directly contribute to the company's success. We realize that our strength and competitive advantage lie with our people. We support our employees in several ways to foster a healthy working environment, meaningful work, mobility, networking, and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Duties & Responsibilities

• Conduct and report data from in vitro metabolism studies using various cellular and subcellular systems, e.g. microsomes, hepatocytes, and transfected cells.

• Operate liquid chromatography tandem mass spectroscopy (LC-MS/MS) instrumentation.

• Contribute to establishing and implementing strategies to rapidly onboard new technologies that enable achievement of portfolio goals.

• Utilize advanced, cutting-edge computing systems and automated equipment to accelerate and optimize progression of our investigational compounds through clinical development.

• Comply with all applicable regulations, ensure that work performed in area of responsibility is conducted in a safe and compliant manner, and maintain proper records in accordance with SOPs and policies.

Requirements

• Bachelor’s Degree from an accredited academic institution in Pharmacology, Biology, Chemistry, Biochemistry, or other relevant field of study or equivalent experience in a related field required.

• Experience conducting experiments to evaluate the interaction of molecules with drug metabolizing enzymes would be highly beneficial.

• An understanding of the foundational principles of enzyme kinetics would be advantageous.

• Experience with culturing cells, operating LC/MS systems, and the safe use of radioactivity would be beneficial.

• Experience with AI-based tools and their application to laboratory-based tasks.

• Ability to communicate effectively both orally and in writing in an interdisciplinary environment.

Eligibility Requirements :

• Must be legally authorized to work in the United States without restriction.

• Must be willing to take a drug test and post-offer physical (if required).

• Must be 18 years of age or older.

Compensation Data

The base salary range for this position is $64,200.00 to $96,400.00 USD. The position may be eligible for a role-specific discretionary bonus, relocation assistance, and/or other compensation elements. We continuously review market data and may adjust salary ranges as needed in the future. Actual compensation will be based on job-related factors such as skills, experience, qualifications, and other factors permitted by law. Benefits include medical, dental, and vision coverage, retirement savings opportunities, paid time off, paid holidays, disability and life insurance benefits, and other company-sponsored benefits. For additional information regarding our benefits and Total Rewards offerings, please click here (https://www.boehringer-ingelheim.com/us/careers/explore-our-company/our-total-rewards) .

JOB ID

39136

Job function

Development

Career level

Experienced professionals

Organization

BI Pharmaceuticals, Inc.

Working time

Full-Time

Job flexibility

On-Site

Boehringer Ingelheim is an equal opportunity global employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment, which benefits our employees, patients, and communities. All qualified applicants will receive consideration for employment without regard to a person’s actual or perceived race, including natural hairstyles, hair texture and protective hairstyles; color; creed; religion; national origin; age; ancestry; citizenship status, marital status; gender, gender identity or expression; sexual orientation, mental, physical or intellectual disability, veteran status; pregnancy, childbirth or related medical condition; genetic information (including the refusal to submit to genetic testing) or any other class or characteristic protected by applicable law