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Senior Director - AI

Mayo Clinic

Rochester, MN · HybridFull-time$248–372K/yrSeen 4 days agoSeen in employer's feed 4 days ago

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At a glance

Compensation
$248–372K/yr
Location
Rochester, MNHybrid
Schedule
Full-time
Work Authorization
Not specified

Olive lists jobs from US employers, including remote roles you can work from the United States.

Requirements

Credentials this posting asks for.

Bachelor's degree

Job overview

The Senior Director, AI leads Mayo Clinic DigPath’s engineering and research team, translating organizational vision into validated, deployed digital-biology products. The role owns technical direction, roadmap, delivery, and quality across AI models and platforms, while managing a multidisciplinary team and cross-functional activities. It also oversees departmental AI governance, technology, and operations, partnering with clinical, scientific, enterprise, and site leaders.

Skills & qualifications

RequiredNice to have

Skills

AI/ML EngineeringSoftware EngineeringDigital Team ManagementTechnology Team ManagementSecurity Team ManagementProduct Team Management

Qualifications

Bachelor's in Relevant Field10 Years Related ExperienceMaster's in Related Field

Benefits

Medical Insurance
Dental Insurance
Vision Insurance
401(k) Match

Full job description

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans (https://jobs.mayoclinic.org/benefits/) – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights

  • Medical: Multiple plan options.

  • Dental: Delta Dental or reimbursement account for flexible coverage.

  • Vision: Affordable plan with national network.

  • Pre-Tax Savings: HSA and FSAs for eligible expenses.

  • Retirement: Competitive retirement package to secure your future.

Responsibilities

The Senior Director, AI leads the engineering and research team that builds and delivers Mayo Clinic DigPath's digital-biology technology platforms, accountable for translating the organization's vision into validated, deployed products. Working closely with the Vice President, Digital Biology, the Chief Medical Officer, and the Chief Science Officer, the Senior Director helps shape technical direction and owns its execution—the roadmap, delivery, and technical quality for DigPath's core model and platform portfolio, including foundation and task-specific models, AI Virtual Cells, biological digital twins, and digital biomarker discovery. Directing a multidisciplinary team of AI/ML engineers, software developers, and research scientists, the Senior Director turns clinical and scientific priorities into engineering execution - partnering with the CMO for clinical relevance and the CSO for scientific rigor - to consistently ship breakthrough tools with speed, technical excellence, and unwavering focus on Mayo Clinic's core value: the needs of the patient come first.

The leader's primary responsibility will be managing highly matrixed cross-functional activities and personnel, with oversite for departmental AI governance, technology, and operations. The leader will also work alongside Chairs representing the department across Mayo Clinic, partnering closely with Shield leaders, and coordinating with other enterprise and Site leaders and governance bodies.

This vacancy is not eligible for sponsorship/ we will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.

Qualifications

Bachelor’s degree in a relevant field, such as Business Administration, Computer Science, AI/ML Engineering, Software Engineering, Information Systems, Design, or Health Informatics plus 10 years of related experience, including executive-level management of digital, technology, security, or product teams in complex organizations.

Master's degree in Business, Law, Computer Science, Engineering, Design, Healthcare Administration, or a related field preferred. Experience in integrated healthcare, academic medical centers, or regulated industries preferred.

Exemption Status

Exempt

Compensation Detail

$248,227.20 - $372,361.60/ year. Education, experience and tenure may be considered along with internal equity when job offers are extended.

Benefits Eligible

Yes

Schedule

Full Time

Hours/Pay Period

80

Schedule Details

M-F 8am-5pm This is a hybrid position and must be located within 100 miles of the Rochester, MN Mayo campus with an expectation to work on-site approximately 1-2 days per week.

Weekend Schedule

As business needs dictate

International Assignment

No

Site Description

Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. (https://jobs.mayoclinic.org/alllocations)

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law" (https://www.eeoc.gov/poster) . Mayo Clinic participates in E-Verify (https://www.e-verify.gov/sites/default/files/everify/posters/EVerifyParticipationPoster.pdf) and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Recruiter

Laura Percival

Equal opportunity

As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available.

How this job compares

Set against the 2,115 open Engineering Management jobs on Olive Jobs, counted November 4, 2026.

Pay
  • This posting$248–372K/yr
  • Minnesota median$140–241K/yr39 salary ranges
  • US median$150–264K/yr1,696 salary ranges

This range's midpoint, $310K, is 66% above the Minnesota median midpoint ($187K) — in the top quarter of Engineering Management salary ranges in Minnesota.

Openings
Olive Jobs lists 41 open Engineering Management jobs in Minnesota and 2,115 across the US. 8% of them nationwide are listed as remote or flexible.
Hiring the most in Minnesota
Experience
This posting asks for at least 10 years of experience; Engineering Management postings that state a minimum ask for 8 years at the median (1,819 postings).
Education
This posting asks for a bachelor's degree; 890 of the 2,115 open Engineering Management jobs (42%) ask for a bachelor's degree or higher.

Counted across the open, public US postings on Olive Jobs on November 4, 2026. Pay medians are the middle values of the low ends and of the high ends of postings that list both ends of a range in the same cadence (a yearly salary or an hourly rate); a range's midpoint is halfway between its ends. Pay and experience figures resting on fewer than 20 postings are left out.

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