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Senior / Staff Software Engineer

Autoscience Institute

San Mateo, CAFull-time$300–500K/yrPosted 7mo agoStill listed 6 days ago

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At a glance

Compensation
$300–500K/yr
Location
San Mateo, CA
Schedule
Full-time
Work Authorization
Not specified

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Requirements

Credentials this posting asks for.

Bachelor's degree

Job overview

Autoscience Institute is hiring a Senior / Staff Software Engineer. The Senior/Staff Software Engineer (Technical Lead) will design and develop core systems for autonomous research agents, building reliable backend infrastructure and production systems for large-scale AI experimentation. This role involves leading complex projects, contributing to system architecture, and guiding small engineering teams, working closely with engineers and researchers to translate experimental ideas into robust production systems.

Key focus areas include Lead the design and implementation of core backend and infrastructure systems, Own projects from architecture and design through production deployment, and Write clear technical design documents and drive engineering decisions.

Successful candidates bring Experience Leading Complex Engineering Projects, Experience Acting As A Technical Lead, and Experience Guiding Small Teams Of Engineers. Important skills include Software Design, Architecture Skills, Technical Design Documents, Python, Backend Infrastructure, and Production Infrastructure. Preferred (not required): System Reliability, Scalability, and Observability.

Skills & qualifications

RequiredNice to have

Skills

Software DesignArchitecture SkillsTechnical Design DocumentsPythonBackend InfrastructureProduction InfrastructureGCPCloud InfrastructureSoftware EvolutionMaintainabilitySystem Design TradeoffsCollaborationSystem ReliabilityScalabilityObservability

Qualifications

Experience Leading Complex Engineering ProjectsExperience Acting as a Technical LeadExperience Guiding Small Teams of EngineersExperience Building Backend InfrastructureExperience Operating Backend InfrastructureExperience Building Production InfrastructureExperience Operating Production InfrastructureExperience Working in 24/7 Production EnvironmentsBachelor's Degree in Computer ScienceBachelor's Degree in MathematicsBachelor's Degree in a Related Field5+ Years of Experience Building Production Software Systems

Benefits

Paid Time Off

Full job description

Company Description

At Autoscience Institute, we automate AI research. Recently, we announced the first AI agent to autonomously create peer-reviewed literature (ICLR 2025) and the first AI system to win a Kaggle medal. We are passionate about pushing the boundaries of artificial intelligence and contributing to groundbreaking advancements in the field.

Role Description

This is a full-time on-site role for a Senior or Staff Software Engineer (Technical Lead) located in the San Francisco Bay Area.

In this role, you will lead the design and development of core systems that power autonomous research agents. You’ll be responsible for building reliable backend infrastructure and production systems that support large-scale AI experimentation and research workflows.

We are looking for engineers who have owned complex projects end-to-end, contributed to system architecture, and helped guide small teams of engineers through delivery. You should be comfortable writing high-quality code, producing clear design documents, and making thoughtful technical decisions that shape how systems evolve over time.

You will work closely with both engineers and researchers to translate experimental ideas into robust production systems.

Responsibilities

  • Lead the design and implementation of core backend and infrastructure systems

  • Own projects from architecture and design through production deployment

  • Write clear technical design documents and drive engineering decisions

  • Build and maintain 24/7 production systems supporting autonomous research agents

  • Partner closely with research teams to productionize experimental workflows

  • Guide and collaborate with engineers on system design and implementation

  • Improve system reliability, scalability, and observability

  • Help shape the technical direction of the platform

Qualifications

  • Experience leading complex engineering projects or technical initiatives

  • Experience acting as a technical lead or guiding small teams of engineers

  • Strong software design and architecture skills

  • Demonstrable experience writing clear technical design documents

  • Strong experience with Python

  • Experience building or operating backend or production infrastructure

  • Experience working in 24/7 production environments

  • Experience with Google Cloud Platform (GCP) or similar cloud infrastructure

  • Strong understanding of software evolution, maintainability, and system design tradeoffs

  • Ability to collaborate effectively with both engineers and researchers

  • Bachelor’s degree in Computer Science, Mathematics, or a related field

  • Strong candidates will typically have 5+ years of experience building and operating production software systems, including ownership of projects from design through deployment

Benefits & Perks

  • Our comp is competitive against major LLM frontier lab packages

  • Unlimited PTO and flexible working arrangements

  • Conference attendance and publication support

Our Culture

We're a team of passionate researchers and engineers working to automate scientific discovery. We believe in the power of AI to accelerate scientific discovery and are committed to responsible AI development.

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