Senior Research Scientist - Tan Lab

Job ID: 1168620_RR00126608

Facility: NYU Langone Medical Center

Position Type: Full-Time/Regular

NYU Grossman School of Medicine is one of the nation's top-ranked medical schools. For 175 years, NYU Grossman School of Medicine has trained thousands of physicians and scientists who have helped to shape the course of medical history and enrich the lives of countless people. An integral part of NYU Langone Health (http://nyulangone.org) , the Grossman School of Medicine at its core is committed to improving the human condition through medical education, scientific research, and direct patient care. At NYU Langone Health, equity and inclusion are fundamental values. We strive to be a place where our exceptionally talented faculty, staff, and students of all identities can thrive. We embrace inclusion and individual skills, ideas, and knowledge.

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Position Summary:

We have an exciting opportunity to join our team as a Senior Research Scientist.

The Tan Lab at NYU is recruiting a research scientist. Our mission is to understand how elements of our genome regulate gene expression and its implications for human diseases. We combine machine learning, biological mechanisms, and large-scale data to understand how regulatory elements control transcription factors, 3D genome organization, and transcription.

Our research interests are:

1 1. Building frontier functional genomic foundation models (e.g., C.Origami, Chromnitron) that explore 3D genome organization, transcription factors, and other aspects of genome regulation.

1. Optimize model architectures with biologically informed priors and scale across multi-modal genomic datasets.

2. Leverage genomic foundation models to understand the role of transcriptional regulation in human development and disease.

3. Develop generative models to rationally design DNA sequences for regulatory elements, gene circuits, and other synthetic biology applications.

4. Building agentic systems to automate model creation, training, evaluation, and in silico experiments.

In this role, the successful candidate Responsible for collaborating with Principal Investigators (PI) and working independently within the scientific framework of the PI's laboratory.

Job Responsibilities:

• Performs other related duties as assigned.

• Initiates, interprets, organizes, executes, and coordinates research assignments critical to departments mission.

• Formulates and conducts research on problems of considerable scope and complexity.

• Explores subject area and defines scope and selection of problems for investigation through conceptually related studies or series of projects of lesser scope.

• Makes decisions and recommendations that have a major impact on extensive scientific research activities.

• Develops new ideas that promote current research. Exercises a high degree of creativity, foresight, and mature judgment in planning, organizing, and guiding extensive scientific research programs and activities of outstanding novelty and/or importance.

• May manage the operations of a lab for the Principal Investigator by supervising Post Docs and technicians. Oversees the maintenance and upkeep of all instruments and software used by the laboratory.

• Ensures timely and accurate completion of research projects.

• May provide students with technical guidance, including computational techniques as well as general coding practices.

• May seek grant funding from external sources in support of their independent research projects with consent of the PI and the Department Chair. May participate in writing grant proposals.

• May be responsible research/lab quality control and compliance.

• May develop protocols for the collection and quality of research data.

• Develops research techniques and methodologies.

• May determine and establish laboratory policies, procedures and practices.

• Maintains a thorough knowledge of the advances in specialized fields through attendance of scientific conferences.

• May make significant contributions to scientific papers. Is a resource/ author/ co-author for reports and presentations.

• May provide recommendations for equipment purchases and for the redesign of lab space.

• May coordinate the activity and experimental design between various labs, scientific staff, and collaborators. Identifies and resolves technical problems.

• May serve on internal committees to help further goals of research projects and bring new expertise to the research program.

• May work with the financial analyst to define the lab budget and work with lab staff to keep the lab spending within budgetary constraints.computational biology, computer science, electrical engineering, statistics, biology, or other technical fields.

Minimum Qualifications:

To qualify you must have a PhD and 3 years of experience or equivalent combination of education and experience.

Preferred Qualifications:

Substantial experience from having completed Post Doc training.

PhD in computational biology, computer science, electrical engineering, statistics, biology, or other technical fields.

Experience leading Bio-ML projects in a collaborative environment and mentoring junior researchers.

First-author publications in regulatory genomics. Experience in assisting with grant applications.

Qualified candidates must be able to effectively communicate with all levels of the organization.

NYU Grossman School of Medicine provides its staff with far more than just a place to work. Rather, we are an institution you can be proud of, an institution where you'll feel good about devoting your time and your talents. At NYU Langone Health, we are committed to supporting our workforce and their loved ones with a comprehensive benefits and wellness package. Our offerings provide a robust support system for any stage of life, whether it's developing your career, starting a family, or saving for retirement. The support employees receive goes beyond a standard benefit offering, where employees have access to financial security benefits, a generous time-off program and employee resources groups for peer support. Additionally, all employees have access to our holistic employee wellness program, which focuses on seven key areas of well-being: physical, mental, nutritional, sleep, social, financial, and preventive care. The benefits and wellness package is designed to allow you to focus on what truly matters. Join us and experience the extensive resources and services designed to enhance your overall quality of life for you and your family.

NYU Grossman School of Medicine is an equal opportunity employer and committed to inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration. We require applications to be completed online.

View Know Your Rights: Workplace discrimination is illegal (https://www.eeoc.gov/sites/default/files/2023-06/22-088\_EEOC\_KnowYourRights6.12ScreenRdr.pdf) .

NYU Langone Health provides a salary range to comply with the New York state Law on Salary Transparency in Job Advertisements. The salary range for the role is $65,000.00 - $93,600.00 Annually. Actual salaries depend on a variety of factors, including experience, specialty, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.

To view the Pay Transparency Notice, please click here (https://cdn-static.findly.com/wp-content/uploads/sites/290/2017/04/pay-transp\_formattedESQA508c.pdf)