Senior Director, Pharma Toxicology

Bausch + Lomb (NYSE/TSX: BLCO) is a leading global eye health company dedicated to protecting and enhancing the gift of sight for millions of people around the worldfrom the moment of birth through every phase of life. Our mission is simple, yet powerful: helping you see better, to live better.

Our comprehensive portfolio of over 400 products is fully integrated and built to serve our customers across the full spectrum of their eye health needs throughout their lives. Our iconic brand is built on the deep trust and loyalty of our customers established over our 170-year history. We have a significant global research, development, manufacturing and commercial footprint of approximately 13,000 employees and a presence in approximately 100 countries, extending our reach to billions of potential customers across the globe. We have long been associated with many of the most significant advances in eye health, and we believe we are well positioned to continue leading the advancement of eye health in the future.

Objectives:

The Senior Director, Pharma Toxicology, is the enterprise leader for nonclinical safety across the Bausch + Lomb pharmaceutical, over-the-counter, and consumer portfolio. Reporting to R&D leadership, this role sets the global nonclinical safety strategy, leads and develops the toxicology organization, and serves as the company's senior scientific authority on toxicology for development programs, lifecycle management, business development, and interactions with health authorities. The Senior Director partners with R&D, Regulatory, Clinical, Quality, and Commercial leadership to ensure that nonclinical strategies enable portfolio decisions, accelerate development timelines, and protect patients and the business.

Responsibilities:

Strategic Leadership

• Define and own the global nonclinical safety and toxicology strategy for pharmaceuticals, over-the-counter products, and consumer goods, aligned with the R&D portfolio and corporate objectives.

• Act as the company's senior subject matter expert in toxicology, representing Bausch + Lomb in meetings with the FDA and other global health authorities and leading nonclinical strategy for key regulatory milestones (e.g., pre-IND, IND, end-of-phase, NDA/MAA, and post-approval).

• Lead nonclinical due diligence for in-licensing, acquisition, and partnership opportunities, and advise senior leadership on nonclinical risks and integration requirements.

• Anticipate evolving regulatory guidance, scientific advances, and industry standards (including New Approach Methodologies and alternatives to animal testing); assess portfolio-wide impact and drive adoption where appropriate.

Organizational & People Leadership

• Build, lead, and develop a high-performing toxicology organization; set goals, manage performance, and drive succession and talent planning.

• Foster a culture of scientific excellence, accountability, and collaboration; coach and mentor team members to support their scientific and professional growth.

• Establish strategic relationships with Contract Research Organizations (CROs) and external experts; oversee vendor selection, contracting, performance, and study quality (including GLP compliance).

Program Execution & Governance

• Oversee the design, execution, interpretation, and communication of nonclinical safety programs to enable clinical development, regulatory submissions/registrations, product launch, ongoing market support, and compliance activities.

• Provide final scientific review and approval of nonclinical sections of regulatory submissions, safety assessments, and technical reports; ensure scientific rigor and consistency across the portfolio.

• Partner with executive and cross-functional leadersincluding Product Development, Clinical Development, Analytical Chemistry, Regulatory Affairs, Quality, Compliance, and Commercialto align nonclinical plans with program and business objectives.

• Direct collaboration with international company sites to address nonclinical safety requirements for country-specific submissions, registrations, and ongoing business needs.

• Lead the development, implementation, and continuous improvement of global departmental processes, standards, and best practices, and drive harmonization across sites.

• Represent Bausch + Lomb externally through scientific publications, conference presentations, and industry consortia, enhancing the company's scientific reputation.

Requirements:

• Ph.D. in Toxicology or related discipline.

• 15+ years of relevant pharmaceutical industry experience in nonclinical safety/toxicology.

• People leadership experience, including leading managers and building or scaling teams.

• Demonstrated track record of setting nonclinical strategy for multiple programs from discovery through registration and lifecycle management, including direct interaction with the FDA and/or other global health authorities.

• Deep knowledge of global nonclinical regulatory requirements and guidance (e.g., ICH) and GLP regulations.

• Experience managing departmental budgets and strategic CRO/vendor relationships.

• Proven ability to influence senior leadership and communicate complex scientific risk clearly to executive and non-technical audiences.

• Experience in ophthalmology drug development is highly desirable.

• DABT preferred.

This position may be available in the following location(s): [[location_obj]]

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status.

For U.S. locations that require disclosure of compensation, the starting pay for this role is between $225,000.00 to $300,000.00 per year. The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors.

U.S. based employees may be eligible for short-term and/or long-term incentives. They may also be eligible to participate in medical, dental, vision insurance, disability and life insurance, a 401(k) plan and company match, a tuition reimbursement program (select degrees), company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive sick time, floating holidays and paid vacation.

Job Applicants should be aware of job offer scams perpetrated through the use of the Internet and social media platforms.

To learn more please readBausch + Lomb's Job Offer Fraud Statement (https://performancemanager.successfactors.eu/doc/custom/BauschLomb/Bausch\_job\_posting\_statement.docx)

Our US Benefit Programs Employee Benefits: Bausch + Lomb (https://www.bausch.com/careers/benefits/)

Applicants must be authorized to work for ANY employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.

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