Senior Director, R&D Strategy Execution & Transformation

General Description:

BeOne Medicines is seeking a highly capable, hands-on leader to drive strategic initiatives and transformation across its global Research & Development organization.

Reporting to the VP of R&D Strategy & Operations, this individual will translate R&D strategic priorities into tangible outcomes, lead complex cross-functional initiatives, establish effective program management structures, and strengthen organizational execution.

The ideal candidate combines strategic problem-solving with exceptional operational discipline, strong business judgment, and the ability to influence stakeholders across a global, matrixed organization. This is a highly visible role with the opportunity to shape how BeOne executes its R&D strategy and accelerates the development of innovative medicines.

Essential Functions of the Job:

Strategic Initiative Execution & Transformation

• Lead high-priority R&D transformation initiatives from strategy through implementation, ensuring measurable outcomes.

• Establish and lead strategic program management offices (PMOs), including workstream design, milestones, governance, risk management, and performance tracking.

• Drive cross-functional alignment and accountability across Research, Development, and enabling functions; proactively resolve issues and escalate critical decisions.

• Identify opportunities to improve R&D operating models, processes, organizational effectiveness, and productivity; design and implement sustainable solutions.

Governance & Operational Excellence

• Support the design and continuous improvement of R&D governance, strategic planning, goal-setting, and performance management processes.

• Establish practical management systems and operating cadences that strengthen decision-making, transparency, and follow-through.

• Partner with functional leaders to translate R&D-wide priorities into actionable plans, clear ownership, and measurable outcomes.

Executive Engagement & Strategic Support

• Partner with R&D leadership to address complex strategic and operational challenges.

• Develop compelling executive communications, decision materials, and progress updates that translate complex information into actionable insights.

• Support leadership forums, strategic reviews, and high-priority activities of the R&D head office.

• Contribute to strategic problem-solving and new initiatives as organizational priorities evolve.

Qualifications & Experience

• Experience in biopharma, life sciences consulting, corporate strategy, transformation, R&D operations, or related fields; consulting and industry experience are equally valued.

• Strong understanding of the pharmaceutical/biotechnology industry and R&D value chain; direct drug development or oncology experience is a plus.

• Demonstrated success independently leading complex cross-functional initiatives, transformations, PMOs, or organizational change programs through implementation.

• Exceptional ability to translate ambiguous objectives into structured workplans and drive execution through stakeholders without direct authority.

• Strong analytical, problem-solving, organizational, and project management skills, with excellent attention to detail and follow-through.

• Excellent executive communication and story-lining capabilities, including the ability to independently develop senior leadership materials.

• High emotional intelligence, sound judgment, and the ability to navigate complex global and matrixed organizations.

• Entrepreneurial, proactive, hands-on, and adaptable; comfortable operating in a fast-paced environment with evolving priorities.

• Bachelor's degree required; advanced degree preferred.

What Success Looks Like

• Critical R&D initiatives advance with clear ownership, disciplined execution, and measurable results.

• R&D leadership has greater visibility into priorities, progress, risks, and decisions.

• Cross-functional teams are better aligned, and strategic decisions translate into sustained organizational change.

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Education Required:

PhD with 6 years of experience or a master’s degree with 8 years of experience preferred.

*exceptions might be made for candidates with relevant experience

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.