Skip to main content
Cardinal Health logo

Senior AI Agentic App Sec Engineer

Cardinal Health

Remote · USFull-time$125–179K/yrSeen todaySeen in employer's feed today

Most applications go out cold — see where you stand first. No sign-up to start.

You apply on the employer's site, with no Olive account needed.

Watch jobs like this.

Don't just apply. Show up ready.

Olive works from this exact posting.

At a glance

Compensation
$125–179K/yr
Location
Remote · US
Schedule
Full-time
Work Authorization
Not specified

Olive lists jobs from US employers, including remote roles you can work from the United States.

Job overview

The Application Security Engineer, AI and Agentic Security designs, prototypes, evaluates, and operationalizes generative and agentic AI capabilities for Application Security. The senior individual contributor combines software engineering, application security, and AI-enabled development to support secure vulnerability analysis, remediation, validation, and workflow automation. The role partners across security, engineering, platform, architecture, and governance teams to move experiments into governed, measurable, and supportable enterprise capabilities.

Skills & qualifications

RequiredNice to have

Skills

Python Development, nice to haveAPI Integration, nice to haveAutomation, nice to haveTesting, nice to haveGenerative AI, nice to haveLarge Language Models, nice to haveRetrieval-Augmented Generation, nice to haveTool Calling, nice to haveWorkflow Orchestration, nice to haveAgent Frameworks, nice to haveAgentic Workflow Design, nice to haveSecure Software Development, nice to haveApplication Security, nice to haveThreat Modeling, nice to haveSecure Design, nice to haveAuthentication and Authorization, nice to haveSecrets Management, nice to haveSoftware Supply Chain Security, nice to haveSAST, nice to haveSCA, nice to haveSecrets Detection, nice to haveDAST, nice to haveAPI Security, nice to haveContainer Security, nice to haveIaC Security, nice to haveVulnerability Remediation, nice to haveGit, nice to haveCI/CD, nice to haveContainers, nice to haveKubernetes, nice to haveCloud-Native Development, nice to haveAI Output Evaluation, nice to haveRed-Team Testing, nice to haveAI Security, nice to havePrompt Injection Mitigation, nice to haveData Leakage Prevention, nice to haveTechnical Writing, nice to havePresentation, nice to haveCross-Functional Collaboration, nice to haveProblem-Solving, nice to have

Qualifications

Bachelor's in Related Field or Equivalent, nice to haveSubstantial Technical Discipline Experience, nice to havePython Proficiency, nice to haveJava or JavaScript/TypeScript or .NET/C# or Go, nice to haveCloud and Kubernetes Experience, nice to haveAI Evaluation or Red Teaming Experience, nice to haveOWASP and NIST Guidance Knowledge, nice to haveCISSP or CSSLP or CCSP or GWEB or Cloud Certification, nice to have

Benefits

Medical Insurance
Dental Insurance
Vision Insurance
Paid Time Off
401(k) Match
Parental Leave

Full job description

Country-wide Remote

US-Nationwide-FIELD

Full time

20190821

Department Overview

The Information Security organization is advancing Application Security to help the enterprise deliver products and services securely as software development practices rapidly evolve. The Application Security Engineering and Innovation team builds, integrates, operates, and matures modern security capabilities across the software development lifecycle, with a particular focus on automation, developer experience, software supply chain security, and AI-enabled security engineering.

Job Overview

The Application Security Engineer, AI and Agentic Security is a senior individual contributor responsible for designing, prototyping, evaluating, and operationalizing generative and agentic AI capabilities within Application Security. The role combines hands-on software engineering, Application Security expertise, and practical experience with AI-enabled development patterns. It will help establish safe, scalable approaches for AI-assisted vulnerability identification, code analysis, remediation, validation, and security workflow automation.

This engineer will partner with Application Security, software engineering, cloud and platform teams, Security Architecture, AI Governance, and other information security functions to move promising concepts from experimentation into governed, supportable enterprise capabilities. The role is expected to balance innovation with disciplined engineering, security controls, measurable outcomes, and long-term operational sustainability.

Responsibilities

  • Design, build, and test prototypes and production-ready capabilities using generative AI, large language models, AI agents, and multi-step agentic workflows.

  • Develop Python-based services, automation, integrations, evaluation harnesses, and supporting tools for Application Security use cases.

  • Evaluate AI-enabled security products and frameworks for vulnerability discovery, exploitability analysis, secure code guidance, remediation, validation, and developer workflow integration.

  • Create controlled workflows in which AI capabilities can analyze code, use approved tools, recommend or generate changes, execute tests, and produce auditable evidence while maintaining appropriate human oversight.

  • Establish technical guardrails for agent identity, least privilege, data access, tool use, repository access, secrets handling, logging, traceability, change control, and safe failure or termination.

  • Develop test plans and benchmarks to assess accuracy, security, reliability, repeatability, cost, latency, false positives, remediation quality, and operational value.

  • Perform security testing of AI and agentic workflows, including prompt injection, unsafe tool use, excessive agency, data leakage, insecure output handling, dependency and supply chain risks, and authorization failures.

  • Integrate capabilities with source control, CI/CD pipelines, developer tools, issue management, security testing platforms, and vulnerability management workflows.

  • Define reference architectures, reusable patterns, technical requirements, runbooks, and operational support models for approved capabilities.

  • Partner with governance and architecture teams to ensure solutions align with enterprise AI, security, privacy, data protection, and technology standards.

  • Support pilots with application teams, capture feedback, measure outcomes, and recommend whether capabilities should be scaled, redesigned, purchased, built, or retired.

  • Maintain awareness of developments in generative AI, agentic systems, secure AI engineering, Application Security, and software delivery practices.

  • Strong hands-on Python development experience, including API integration, automation, testing, data handling, and production-quality engineering practices.

  • Experience building or integrating solutions using large language models, model APIs, retrieval-augmented generation, tool calling, structured outputs, workflow orchestration, or agent frameworks.

  • Experience designing and evaluating agentic workflows that use tools, maintain state, make bounded decisions, and operate with human approval where appropriate.

  • Strong understanding of secure software development, common application vulnerabilities, threat modeling, secure design, authentication and authorization, secrets management, and software supply chain risk.

  • Experience with Application Security capabilities such as SAST, SCA, secrets detection, DAST, API security, container security, IaC security, and vulnerability remediation workflows.

  • Experience with Git-based development, pull requests, CI/CD, automated testing, containers, Kubernetes, and cloud-native development patterns.

  • Ability to evaluate AI output quality using repeatable test cases, metrics, red-team scenarios, and evidence-based comparison rather than demonstration results alone.

  • Understanding of AI security risks and controls, including prompt injection, data leakage, excessive agency, insecure tool use, model and dependency supply chain risk, and auditability.

  • Strong problem-solving, technical writing, presentation, and cross-functional collaboration skills.

  • Ability to move between experimental engineering and enterprise operationalization without losing sight of maintainability, governance, cost, and support requirements

Qualifications

  • Bachelor's degree in computer science, software engineering, cybersecurity, information systems, or a related field, or equivalent practical experience.

  • Substantial experience in software engineering, security engineering, Application Security, DevSecOps, or a closely related technical discipline.

  • Demonstrated proficiency developing solutions in Python.

  • Demonstrated understanding of Application Security concepts and secure software development practices.

  • Experience delivering complex technical work with limited definition and coordinating across multiple stakeholder groups.

  • Hands-on experience with generative AI application development, LLM integration, agentic systems, or AI-enabled developer tooling.

  • Experience with one or more additional languages or platforms such as Java, JavaScript/TypeScript, .NET/C#, or Go.

  • Experience with cloud services, containers, Kubernetes, infrastructure as code, and enterprise developer platforms.

  • Experience with AI evaluation, adversarial testing, red teaming, observability, or governance controls for AI-enabled systems.

  • Knowledge of industry guidance such as the OWASP Top 10, OWASP guidance for LLM or agentic applications, NIST Secure Software Development Framework, and NIST AI Risk Management Framework.

  • Relevant security, cloud, or software credentials are beneficial but not required; examples may include CISSP, CSSLP, CCSP, GWEB, or cloud-provider certifications.

What Is Expected of You and Others at This Level

  • Applies advanced knowledge of software engineering, Application Security, and AI-enabled development to solve complex and ambiguous problems.

  • Leads or materially contributes to complex projects with broad scope, significant technical impact, and long-term operational implications.

  • Recommends new practices, architectures, controls, metrics, and engineering approaches for emerging capabilities.

  • Independently determines methods for completing new or undefined work while receiving guidance on overall objectives.

  • Experience in providing solutions and technical patterns that help establish precedents for organization wide adoption .

  • Experience in transiting emerging technology into practical, secure, and supportable capabilities that can be adopted by engineering teams.

  • Efficiently communicate technical findings, risks, trade-offs, and recommendations to engineering, security, governance, in various leadership forums.

  • Acts as a mentor and technical resource for less experienced colleagues and cross-functional partners.

Success in This Role

Success is demonstrated by converting emerging AI capabilities into secure, measurable, and operationally sustainable Application Security outcomes. The strongest candidate will be equally comfortable writing and testing code, challenging the safety and effectiveness of an AI workflow, explaining trade-offs to leadership, and partnering with platform and application teams to move a capability into responsible enterprise use

Anticipated salary range: $125,300 - $178,900

Bonus eligible: Yes

Benefits: Cardinal Health offers a wide variety of benefits and programs to support health and well-being.

  • Medical, dental and vision coverage

  • Paid time off plan

  • Health savings account (HSA)

  • 401k savings plan

  • Access to wages before pay day with myFlexPay

  • Flexible spending accounts (FSAs)

  • Short- and long-term disability coverage

  • Work-Life resources

  • Paid parental leave

  • Healthy lifestyle programs

Application window anticipated to close: 12/23/2026 *if interested in opportunity, please submit application as soon as possible.

The salary range listed is an estimate. Pay at Cardinal Health is determined by multiple factors including, but not limited to, a candidate’s geographical location, relevant education, experience and skills and an evaluation of internal pay equity.

Cardinal Health supports an inclusive workplace that values diversity of thought, experience and background. We celebrate the power of our differences to create better solutions for our customers by ensuring employees can be their authentic selves each day. Cardinal Health is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, ancestry, age, physical or mental disability, sex, sexual orientation, gender identity/expression, pregnancy, veteran status, marital status, creed, status with regard to public assistance, genetic status or any other status protected by federal, state or local law.

To read and review this privacy notice click here (https://www.cardinalhealth.com/content/dam/corp/email/documents/corp/cardinal-health-online-application-privacy-policy.pdf)

Headquartered in Dublin, Ohio, Cardinal Health, Inc. (NYSE: CAH) is a distributor of pharmaceuticals, a global manufacturer and distributor of medical and laboratory products, and a provider of performance and data solutions for healthcare facilities.

We are a crucial link between the clinical and operational sides of healthcare, delivering end‑to‑end solutions and data‑driving insights that advance healthcare and improve lives every day. With deep partnerships, diverse perspectives and innovative digital solutions, we build connections across the continuum of care.

With more than 50 years of experience, we seize the opportunity to address healthcare's most complicated challenges — now, and in the future.

View Cardinal Health on YouTube (http://youtube.com/user/CardinalHealth)

How this job compares

Set against the 41,410 open Software Engineer jobs on Olive Jobs, counted November 10, 2026.

Pay
  • This posting$125–179K/yr
  • Nevada median$122–231K/yr242 salary ranges
  • US median$135–219K/yr32,963 salary ranges

This range's midpoint, $152K, is 13% below the Nevada median midpoint ($175K) — in the middle half of Software Engineer salary ranges in Nevada.

Openings
Olive Jobs lists 256 open Software Engineer jobs in Nevada and 41,410 across the US. 8% of them nationwide are listed as remote or flexible.
Hiring the most in Nevada
Experience
Software Engineer postings that state a minimum ask for 5 years of experience at the median; the middle half ask for 3 to 7 years (33,915 postings).
Education
12,935 of the 41,410 open Software Engineer jobs (31%) ask for a bachelor's degree or higher.

Counted across the open, public US postings on Olive Jobs on November 10, 2026. Pay medians are the middle values of the low ends and of the high ends of postings that list both ends of a range in the same cadence (a yearly salary or an hourly rate); a range's midpoint is halfway between its ends. Pay and experience figures resting on fewer than 20 postings are left out.

Prepare for this role

You've read the whole posting — now see how you match it.