GSOM DirectorOrganoid Facility

NYU Grossman School of Medicine is one of the nation's top-ranked medical schools. For 175 years, NYU Grossman School of Medicine has trained thousands of physicians and scientists who have helped to shape the course of medical history and enrich the lives of countless people. An integral part of NYU Langone Health, the Grossman School of Medicine at its core is committed to improving the human condition through medical education, scientific research, and direct patient care. At NYU Langone Health, equity and inclusion are fundamental values. We strive to be a place where our exceptionally talented faculty, staff, and students of all identities can thrive. We embrace inclusion and individual skills, ideas, and knowledge. For more information, go tomed.nyu.edu, and interact with us on LinkedIn, Glassdoor, Indeed, Facebook, XandInstagram.Position Summary:We have an exciting opportunity to join our team as a GSOM Director-Organoid Facility. The Institute for Regenerative Medicine seeks an accomplished and collaborative Director to lead the development, implementation, and expansion of a state-of-the-art organoid core. The Director will be responsible for establishing robust organoid and gene editing workflows that directly support investigator needs, building standardized and scalable operating procedures, ensuring rigorous quality control, and expanding facility capabilities over time. This role will require close partnership with faculty, laboratory personnel, and institutional core facilities to create a highly responsive, efficient, and scientifically rigorous resource that advances regenerative medicine.Job Responsibilities:1. Establish and implement foundational organoid platformsWork closely with the initial group of priority investigators to assess and meet their organoid-related research needs.Establish organoid protocols for at least one lineage derived from each of the three germ layers.Develop these three germ layer organoid systems in parallel to build broad foundational capability efficiently.Interface directly with individual laboratories to ensure protocols are optimized for their scientific and experimental needs.Translate laboratory-specific SOPs into standardized Core SOPs that support reproducibility, scalability, and shared facility operations.Implement all necessary cell line tracking, documentation, and quality control procedures to support rigorous and reliable core operations.2. Build gene editing capabilities within the facilityObtain and evaluate gene editing protocols from key internal and external collaborators.Work directly with relevant laboratory personnel, including postdoctoral fellows, to adapt and refine protocols for facility implementation.Engage with high-performing external gene editing programs to identify operational best practices and efficient models that could inform facility development.Establish gene editing workflows that can be deployed in support of investigator projects.Finalize standardized SOPs for gene editing services within the facility.Partner with the NYU Genome Engineering Core to explore opportunities for cross-training personnel and leveraging existing institutional expertise and resources.3. Introduce automation to enhance throughput and efficiencyAfter the needs of the initial faculty users have been successfully met and foundational workflows are operating effectively, identify opportunities to introduce automation into high-throughput processes.Develop automation strategies for applications such as qPCR workflows, 96-well organoid generation, and other scalable processes as appropriate.Evaluate and implement technologies that improve efficiency, reproducibility, and capacity while maintaining high scientific quality.4. Expand facility services and institutional engagementBroaden the facility's service offerings to support additional investigators across NYULH.Develop and implement regular training programs for users, including faculty, trainees, an