Head of Clinical Affairs
San Francisco, CAFull-timePosted 1w agoStill listed 1 day ago
Most applications go out cold — see where you stand first. No sign-up to start.
You apply on the employer's site, with no Olive account needed.
Watch jobs like this. New roles like this one near San Francisco, CA, by email.
Don't just apply. Show up ready.
Olive works from this exact posting.
At a glance
Olive lists jobs from US employers, including remote roles you can work from the United States.
Job overview
Coherence Neuro is seeking a Head of Clinical Affairs to build and execute early clinical strategy for its neurotechnology pipeline. The role works closely with translational and data science teams, regulatory and quality functions, clinical advisors, CROs, and investigators. The ideal candidate has prior experience leading multiple clinical trials from protocol development through study closeout.
Skills & qualifications
Skills
Qualifications
Full job description
Head of Clinical Affairs
Job Title: Head of Clinical Affairs
Location: San Francisco
Type: Full-Time (on-site)
Click here to apply
Coherence Neuro is a highly interdisciplinary neurotechnology company solving some of the most challenging biological and medical problems that remain unmet. Our goal is to develop technologies that significantly increase the quality and length of life for those with debilitating and deadly cancers in the brain and body. We are backed by the best global venture capital firms, and are scaling our team across multiple sites to bring our products to those who need it as quickly and safely as possible. If you're driven to push the boundaries of engineering and science and want to help build something that genuinely changes lives, we want to hear from you. We value diversity and encourage applicants from all backgrounds to join us in our mission. Learn about our team here!
We are building a robust clinical pipeline and looking for a detail-orientated and ambitious Head of Clinical Affairs who is passionate about building the early clinical strategy and putting it into action. The successful candidate will work closely with Translational Science, Data Science, Regulatory, Quality, surgical and clinical advisors, CROs and investigators. The ideal candidate will have prior experience leading multiple clinical trials from protocol development to study close out.
Key Responsibilities
Establish the clinical development plan for FIH and early feasibility.
Integrate existing preclinical, bench, risk-management and reimbursement strategy evidence into clinical protocols that inform therapy safety and efficacy.
Own clinical content of the investigator's brochure, informed-consent materials, CRFs and clinical risk analysis.
Partner with Data Science on statistical and neural-data analysis plans, data reviews and interpretation of results.
Lead ongoing review of clinical, safety, laboratory and operational data to identify trends, risks and data-quality issues.
Ensure sponsor obligations are met, including safety reporting, regulatory and ethics notifications, and sponsor files and the trial master file.
Lead study start-up through close-out
Set the CRO and vendor strategy, deciding what to keep in-house versus outsource, and lead vendor selection and oversight.
Define clinical evidence requirements for regulatory/ethicssubmissions
Lead clinical sections of regulatory submissions and pre-submission meetings
Build relationships with key opinion leaders, hospitals and patient advocacy groups..
Work with the CSO and surgical advisor to establish and run surgical, neuro-oncology and radio-oncology advisory boards.
Lead investigator meetings, scientific training and responses to clinical questions from sites.
Develop the reporting and publication plan: clinical study reports, abstracts, presentations and manuscripts.
Establish standard operating procedures and workfows for clinical function.
How this job compares
Set against the 497 open Clinical Development jobs on Olive Jobs, counted November 10, 2026.
- Pay
- This postingNot listed
- California median$253–327K/yr64 salary ranges
- Openings
- Olive Jobs lists 76 open Clinical Development jobs in California and 497 across the US. 10% of them nationwide are listed as remote or flexible.
- Hiring the most in California
- Gilead Sciences, Inc.22 open
- AbbVie7 open
- BeOne Medicines6 open
- Experience
- Clinical Development postings that state a minimum ask for 6 years of experience at the median; the middle half ask for 5 to 7 years (427 postings).
- Education
- 326 of the 497 open Clinical Development jobs (66%) ask for a bachelor's degree or higher.
Counted across the open, public US postings on Olive Jobs on November 10, 2026. Pay medians are the middle values of the low ends and of the high ends of postings that list both ends of a range in the same cadence (a yearly salary or an hourly rate); a range's midpoint is halfway between its ends. Pay and experience figures resting on fewer than 20 postings are left out.
Prepare for this role
You've read the whole posting — now see how you match it.
