Mechanical Engineer - Consumables

Cellino Biotech, Inc. is an innovation- and value-driven, venture-capital-backed biotechnology company pioneering a transformative platform for manufacturing cell-based therapies. The company was founded by a team of interdisciplinary, entrepreneurial scientists and engineers with expertise in laser physics, biology, software development, optics, precision instrumentation, and business. The Mechanical Engineer – Consumables and Fabrication role owns the design and manufacturability of consumables that support Cellino's manufacturing platform, including single-use fluidic assemblies and cell-culturing chambers, and supports the mechanical design and fabrication of the platform itself. This person will design and improve components, fixtures, and tooling, and bring a manufacturing engineering mindset to scaling these designs from R&D prototypes toward reliable, repeatable production. The ideal candidate is a mechanical engineer who enjoys both design and hands-on build work, consistently seeks ways to improve designs and streamline operations, uses AI tools to work faster and smarter, and communicates clearly with engineers, scientists, technicians, and leadership. This is a full-time, in-person engineering role. The Mechanical Engineer will be a member of the engineering group and report to Blair Morad, Senior Director of Engineering. Responsibilities

• Design, prototype, and iterate mechanical components and assemblies for single-use fluidic assemblies and cell culturing chambers
• Drive design-for-manufacturability and design-for-assembly improvements to consumables and cell culturing chambers in collaboration with R&D and other engineering teams
• Design fixtures, jigs, and tooling that improve throughput, yield, and consistency of assembly
• Perform engineering analysis to support design decisions, including tolerance analysis, materials selection, and design verification testing
• Own manufacturing processes for consumables and cell culturing chambers, from component preparation through assembly, inspection, and release
• Define and track process metrics such as yield, cycle time, and scrap, and use data to identify and prioritize improvements
• Develop inspection and test methods, including acceptance criteria, leak and pressure testing, and dimensional inspection
• Lead root-cause investigations of design and build failures, and implement corrective actions
• Create and maintain engineering drawings, specifications, PFMEAs, test protocols, SOPs, and technical reports
• Select and qualify components and suppliers, and define specifications for purchased and custom parts
• Plan and support scale-up of consumable and cell culturing chamber production, including preparation for future GMP manufacturing
• Support mechanical design, fabrication, and integration of platform subsystems, including definition of cable and harness builds
• Leverage AI tools and agentic workflows to accelerate design iteration, documentation, data analysis, and process automation
• Direct and train technicians and contract assemblers on assembly processes and quality standards
• Present technical findings, design proposals, and recommendations to cross-functional teams and leadership

Requirements

• BS in Mechanical Engineering or a closely related field with 1-5 years of experience in single-use consumable manufacturing.
• Experience designing mechanical components or assemblies through prototype and build, ideally in medical devices, bioprocess, or life science instrumentation
• Proficiency in CAD (e.g., SolidWorks) and the ability to create engineering drawings using GD&T
• Working knowledge of tolerance analysis, materials selection, and design for manufacturing and assembly
• Hands-on prototyping, build, and fixture design experience
• Familiarity with process improvement and problem-solving methods (e.g., root-cause analysis, PFMEA, Lean)
• Comfort analyzing data to drive decisions (Excel, Python, JMP, Minitab, or similar)
• Experience using AI tools and agentic workflows to support engineering work, such as design exploration, documentation, analysis, or task automation
• Excellent verbal and written communication skills, including the ability to present technical work clearly to technical and non-technical audiences
• Organized and reliable, with an ability to work independently, deliver results consistently, and take ownership and responsibility for their work scope

Nice to Have

• Manufacturing engineering experience, including process development and scale-up
• Experience with single-use bioprocess components (tubing, bags, connectors), cell culturing chambers, or microfluidic devices
• Experience designing plastic parts for injection molding or other high-volume manufacturing processes
• Exposure to GMP, ISO 13485, design controls, or process validation (IQ/OQ/PQ)
• Cell culture or aseptic technique experience
• Experience with writing and interpreting Python code for automation and data analysis
• Proficient with microscopes and other optical and mechanical measuring systems
• Familiarity with lab automation equipment

Actual compensation is determined based on experience, education, role-specific competencies, internal equity with employees in similar positions, and employer-verified market data provided by an independent third-party partner. In addition to base salary, Cellino offers a comprehensive benefits package that includes equity compensation, medical, dental, and vision coverage, childcare support, a family leave program, flexible time off, commute subsidies, and more.

Equal Opportunity Statement It is the policy of Cellino Biotech, Inc. to provide equal employment opportunity for all applicants and employees. The Company does not unlawfully discriminate on the basis of race, religion, creed, color, national origin, ancestry, physical and/or mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, transgender status, pregnancy, marital status, age, sexual orientation, and military or veteran status, or any other basis protected by law. It also prohibits unlawful discrimination and harassment based on the perception that anyone has any of those characteristics or is associated with a person who has or is perceived as having any of those characteristics. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Cellino does not accept unsolicited resumes from any source other than directly from potential candidates. Any resumes submitted by a staffing agency in the absence of a current executed contract will automatically become Cellino's property, and no recruiting fees or other obligations will be owed in the event of a potential hiring.