
Senior Signal Processing Engineer - Biosensor Readout
San Francisco, CAFull-time$140–200K/yrSeen 1 day agoStill listed 1 day ago
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At a glance
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Job overview
Numen is building diagnostic technology for earlier disease detection. The Senior Signal Processing Engineer owns the measurement chain from sensor to reported result, including readout electronics, signal processing, and algorithms that convert raw sensor data into quantitative outputs. The role defines sensor-array readout architecture, develops and validates algorithms, characterizes instrument performance, and supports verification and design-history documentation.
Skills & qualifications
Skills
Qualifications
Full job description
About Numen Numen is a San Francisco-based team building technology to drive cancer mortality toward zero. Our goal is to compress every patient's journey from the first signal of disease to optimal treatment with earlier, easier detection. Backed by Y Combinator, we are a dynamic team across bioscience, engineering, machine learning, and design, building diagnostics from the ground up. About the role This role owns the measurement chain from sensor to reported result: readout electronics, signal processing, and the algorithms to turn raw sensor data into a quantitative output. What you'll do
- Define readout architecture for sensor arrays: excitation, lock-in/demodulation, ADC selection, noise budgeting
- Develop and validate signal processing and calibration algorithms (drift correction, temperature compensation, baseline estimation, multiplex deconvolution)
- Characterize noise sources and set instrument specifications from assay requirements.
- Implement algorithms in firmware and/or host software with version control, unit tests, and traceability to requirements
- Specify and execute analytical verification: precision, linearity, interference, and robustness studies per CLSI guidance
- Support hardware V&V, design reviews, and DHF content for software and algorithm components (IEC 62304)
Requirements
- MS or PhD in Electrical Engineering, Physics, or related field
- 5+ years developing signal acquisition and processing for medical or scientific instruments, with at least one product through FDA clearance
- Low-noise analog design and mixed-signal system experience
- Python and C/C++ (or Rust)
- Experience defining and running analytical performance studies
Nice to have
- IVD or point-of-care diagnostics experience
Why Join Us:
- Be part of a visionary team that is set to change the way diagnostic testing is done.
- Work in a collaborative and innovative environment with leading experts across various fields.
- Competitive salary and benefits package.
- Opportunities for professional growth and development in a fast-paced startup setting.
- Make a tangible impact on healthcare and improve patient outcomes through at-home diagnostics.
Even if you feel like you don’t meet all of the qualifications, we encourage you to apply! Research shows that while men apply to jobs where they meet an average of 60% of the criteria, women and other underrepresented people tend to only apply when they meet 100% of the qualifications. At Cleancard, we welcome diverse perspectives and people who think rigorously and aren't afraid to challenge the status quo. Cleancard is an equal opportunity employer; we celebrate diversity and are committed to creating an inclusive environment, free from discrimination or harassment, for all employees.
How this job compares
Set against the 10,328 open Electrical Engineer jobs on Olive Jobs, counted October 29, 2026.
- Pay
- This posting$140–200K/yr
- California median$129–186K/yr1,031 salary ranges
- US median$108–170K/yr6,607 salary ranges
This range's midpoint, $170K, is 7% above the California median midpoint ($158K) — in the middle half of Electrical Engineer salary ranges in California.
- Openings
- Olive Jobs lists 1,277 open Electrical Engineer jobs in California and 10,328 across the US. 3% of them nationwide are listed as remote or flexible.
- Hiring the most in California
- Anduril Industries80 open
- Anduril69 open
- Jacobs62 open
- Experience
- This posting asks for at least 6 years of experience; Electrical Engineer postings that state a minimum ask for 5 years at the median (8,613 postings).
- Education
- 6,972 of the 10,328 open Electrical Engineer jobs (68%) ask for a bachelor's degree or higher.
Counted across the open, public US postings on Olive Jobs on October 29, 2026. Pay medians are the middle values of the low ends and of the high ends of postings that list both ends of a range in the same cadence (a yearly salary or an hourly rate); a range's midpoint is halfway between its ends. Pay and experience figures resting on fewer than 20 postings are left out.
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