Scientist II - LNP Formulation
San Diego, CAFull-timeSeen 1w agoSeen in employer's feed 1 day ago
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Job overview
The Scientist II will join a formulation team in an onsite laboratory role, executing and optimizing lipid nanoparticle formulations for nucleic acid delivery. The role includes DoE-based screening, characterization, early-stage development, data analysis and presentation, and routine lab management. The posting seeks a candidate with relevant biopharma and LNP experience, analytical proficiency, and strong organizational and communication abilities.
Skills & qualifications
Skills
Qualifications
Full job description
Title: Scientist II - LNP Formulation
Description: Onsite: San Diego, CA. No relocations.
Position Summary
We are seeking a motivated and detail-oriented Scientist 1 to join our Formulation team. In this hands-on laboratory role, you will work closely with senior scientists to execute and optimize the synthesis of targeted and non-targeted lipid nanoparticles (LNPs) for nucleic acid delivery. The successful candidate will be a collaborative team player with strong technical and data analysis skills who is ready to contribute to our non-viral delivery platform.
Responsibilities:
• Execute and optimize the formulation and characterization of lipid nanoparticles (LNPs) or targeted lipid nanoparticle (tLNPs) encapsulating nucleic acids for in vitro and in vivo studies under the minor guidance of senior formulation scientists.
• Implement Design of Experiment (DoE) based screening campaigns to evaluate and establish optimal LNP compositions and processing parameters.
• Collaborate cross-functionally with internal teams to support and fulfill formulation requests.
• Support early-stage formulation development and downstream processing activities when needed, including cryoprotection, scale-up, and stability studies.
• Maintain detailed records documenting formulation activities and results.
• Analyze, interpret, and present experimental data to the formulation team.
• Contribute to routine lab management activities, including inventory tracking, supply ordering, buffer preparation, and autoclaving.
Requirements, Knowledge, Skills, and Abilities:
• Education: Bachelors degree in Chemistry, Biochemistry, Chemical Engineering, or a related discipline with 5+ years of biopharma industry experience, OR a Masters degree with 2+ years of industry experience.
• LNP Expertise: Minimum of 2 years of hands-on laboratory experience specializing in LNP formulation and encapsulation of nucleic acids (mRNA, siRNA, or DNA).
• Analytical Skills: Proficiency with standard LNP characterization methods, including Dynamic Light Scattering (DLS), Zeta potential, and Ribogreen assays.
• Software & Data: High proficiency in MS Excel is required; hands-on experience with statistical and data analysis software (e.g., JMP, Prism) is preferred.
• Core Competencies: Strong attention to detail, a track record of producing reproducible data, excellent organizational skills, and the ability to communicate effectively within a fast-paced team environment.
• Preferred Skills: Prior experience with targeted LNP preparation (mAb, Fab, ScFv, VHH coated LNP) and immune cell delivery is highly desirable.
Motion Recruitment Partners (MRP) is an Equal Opportunity Employer. All applicants must be currently authorized to work on a full-time basis in the country for which they are applying, and no sponsorship is currently available. Employment is subject to the successful completion of a pre-employment screening. Accommodation will be provided in all parts of the hiring process as required under MRP’s Employment Accommodation policy. Applicants need to make their needs known in advance.
How this job compares
Set against the 2,042 open Scientist jobs on Olive Jobs, counted October 30, 2026.
- Pay
- This postingNot listed
- California median$124–174K/yr272 salary ranges
- California median$35–38/hr32 hourly ranges
- Openings
- Olive Jobs lists 432 open Scientist jobs in California and 2,042 across the US. Under 1% of them nationwide are listed as remote or flexible.
- Hiring the most in California
- Genentech30 open
- Amgen24 open
- Cedars-Sinai19 open
- Experience
- This posting asks for at least 2 years of experience; Scientist postings that state a minimum ask for 3 years at the median (1,464 postings).
- Education
- 1,206 of the 2,042 open Scientist jobs (59%) ask for a bachelor's degree or higher.
Counted across the open, public US postings on Olive Jobs on October 30, 2026. Pay medians are the middle values of the low ends and of the high ends of postings that list both ends of a range in the same cadence (a yearly salary or an hourly rate); a range's midpoint is halfway between its ends. Pay and experience figures resting on fewer than 20 postings are left out.
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