
Senior Program Manager, AI Programs
Durham, NCJob$115–165K/yrSeen 3 days agoSeen in employer's feed today
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At a glance
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Job overview
The Senior Program Manager will establish an operating model to coordinate AI-related work across platforms, engineering, product, business stakeholders, and vendors. The role will create governance, roadmaps, reporting, and metrics to support current AI initiatives and a scalable enterprise portfolio. It will also strengthen stakeholder relationships, improve visibility into priorities and risks, and communicate program progress to teams and senior leadership.
Skills & qualifications
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Job Description
Role purpose
The Senior Program Manager will establish the operating model that brings together AI-related work across platforms, engineering, product, business stakeholders, and vendors.
The role will create a scalable foundation that can eventually support a broader enterprise AI portfolio.
Core responsibilities
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Establish the program operating model
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Facilitate agreement on, document, and maintain governance, decision rights, working forums, intake processes, and escalation paths,
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Create a consistent operating rhythm across participating teams.
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Establish a framework that can scale from a single strategic AI platform to a broader portfolio of AI tools and capabilities.
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Create roadmap and prioritization transparency
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Coordinate execution of agreed priorities, cross-team dependencies, and delivery risks.
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Partner with product, platform, and engineering leaders to support roadmap alignment and prioritization.
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Bring business needs and stakeholder feedback into planning discussions.
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Design roadmap practices that can eventually accommodate multiple AI platforms
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Strengthen business and leadership relations
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Build trusted relationships with business stakeholders and represent the AI program clearly.
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Improve visibility into what is available, what is planned, and how stakeholders can engage.
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Prepare clear updates, roadmaps, showcases, and executive communications.
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Serve as a consistent connection point between functional teams, the business, PMO, and senior leadership.
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Establish metrics and reporting
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Define a focused set of standard metrics covering delivery health, adoption, stakeholder satisfaction, risk, and business value.
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Establish reporting cadences for working teams, the PMO, and senior leadership.
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Create a consistent reporting framework that can expand as additional AI platforms and capabilities are introduced.
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Use metrics and feedback to identify improvement opportunities and recommend adjustments.
Success measures
Success will be demonstrated by:
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A clear and consistently used AI program operating model.
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Visible and aligned roadmaps across product, platform, engineering, and adoption.
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Stronger business stakeholder relationships and satisfaction.
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Consistent reporting into the PMO and senior leadership.
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Improved visibility into risks, dependencies, priorities, and decisions.
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A scalable framework for incorporating additional AI platforms over time.
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Clearer evidence of adoption and business value across the AI portfolio.
Soft skills
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Builds trust across technical, business, and leadership teams.
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Communicates clearly and simplifies complex topics.
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Facilitates alignment and influences without direct authority.
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Creates structure in ambiguous environments.
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Demonstrates strong judgment, collaboration, and follow-through.
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Adapts quickly in a changing AI landscape.
Minimum experience
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8+ years in program management, technical project management, product management, or a related field.
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Experience leading complex, cross-functional technology initiatives.
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Experience with AI, enterprise technology, digital transformation, or emerging technologies preferred.
Compensation and Benefits
The salary range estimated for this position based in California is $114,600.00–$165,000.00.
This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
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A choice of national medical and dental plans, and a national vision plan, including health incentive programs
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Employee assistance and family support programs, including commuter benefits and tuition reimbursement
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At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
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Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
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Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.
How this job compares
Set against the 11,207 open Program Manager jobs on Olive Jobs, counted October 27, 2026.
- Pay
- This posting$115–165K/yr
- North Carolina median$123–210K/yr156 salary ranges
- US median$120–203K/yr8,817 salary ranges
This range's midpoint, $140K, is 16% below the North Carolina median midpoint ($166K) — in the middle half of Program Manager salary ranges in North Carolina.
- Openings
- Olive Jobs lists 218 open Program Manager jobs in North Carolina and 11,207 across the US. 4% of them nationwide are listed as remote or flexible.
- Experience
- This posting asks for at least 8 years of experience; Program Manager postings that state a minimum ask for 6 years at the median (9,534 postings).
- Education
- 5,036 of the 11,207 open Program Manager jobs (45%) ask for a bachelor's degree or higher.
Counted across the open, public US postings on Olive Jobs on October 27, 2026. Pay medians are the middle values of the low ends and of the high ends of postings that list both ends of a range in the same cadence (a yearly salary or an hourly rate); a range's midpoint is halfway between its ends. Pay and experience figures resting on fewer than 20 postings are left out.
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