Clinical Trial Manager (CTM) US/Remote

Clinical Trial Manager (CTM) - US/Remote Syneos Health is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress.Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape. Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you'll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver - for one another, our customers, and, most importantly, for those in need. Discover what your 25,000 future colleagues already know: Why Syneos Health* We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.* We are committed to building an inclusive culture - where you can authentically be yourself. Central to this is our purpose - Driven to Deliver - which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone's life. * We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress. Job Responsibilities CLINICAL TRIAL MANAGER (CTM) - US/ Remote Lead Global Clinical Trials | Drive Innovation | Advance Patient Impact At Syneos Health, we bring together clinical development and commercialization expertise to help our customers accelerate the delivery of life-changing therapies. By integrating clinical operations, medical affairs, and commercial insights, we create smarter, faster development pathways-always with patients at the center. We're expanding our Clinical Operations team and are seeking Clinical Trial Managers (CTMs) who are passionate about operational excellence, collaborative leadership, and delivering high-quality global clinical trials. THE ROLE:As a Clinical Trial Manager, you will serve as the operational leader for one or more clinical trials, owning execution from study start-up through closeout. You'll work within a dynamic, matrixed environment-partnering closely with cross-functional teams, sponsors, and sites to ensure timely, compliant, and high-quality trial delivery.This is an opportunity to lead complex studies, influence outcomes, and play a key role in advancing innovative therapies to patients worldwide. WHAT YOU WILL DO: * Lead end-to-end clinical trial execution, ensuring delivery against timelines, quality standards, and budget * Provide operational oversight of site management and monitoring activities, including on-site and centralized monitoring * Identify, assess, and proactively mitigate clinical and operational risks using a risk-based management approach (RACT) * Serve as the primary escalation point for CRAs, investigative sites, and cross-functional stakeholders * Partner closely with Study Start-Up, Data Management, Biostatistics, Safety, and Patient Recruitment teams to drive milestone achievement * Leverage integrated systems and data (CTMS, EDC, ePRO, TMF, dashboards) to monitor performance, trends, and risk indicators * Ensure ongoing inspection readiness and compliance with ICH-GCP, SOPs, and global regulatory requirements * Lead study-specific training and foster alignment across the clinical trial team * Review metrics and operational data to anticipate challenges