Senior Scientist, Gene Therapy Manufacturing

We are hiring for a Senior Scientist in the Gene Therapy field here in Columbus, Ohio! This is a long-term career opportunity and we are looking for someone with at least 5+ years of experience in the Pharmaceutical or Gene Therapy field and a Bachelors or Masters Degree in a scientific field.

Candidates will ideally have experience in upstream or downstream processing, but can be somewhat flexible with that.

Responsibilities

We're seeking an experienced Senior Scientist to lead critical downstream manufacturing activities for viral vector and gene therapy products in a highly regulated cGMP environment. This is an opportunity to apply your expertise in purification, filtration, and formulation while driving process improvements, mentoring team members, and partnering with cross-functional teams to deliver life-changing therapies.

What You'll Do

• Lead downstream manufacturing operations, including chromatography, filtration, ultrafiltration/diafiltration (UF/DF), and viral vector formulation.

• Operate, troubleshoot, and optimize advanced manufacturing equipment, including chromatography, filtration, centrifugation, and TFF systems.

• Monitor process performance, analyze manufacturing data, and resolve process deviations to ensure product quality and operational excellence.

• Perform in-process testing and quality checks, including pH, conductivity, pressure, and other analytical measurements.

• Ensure accurate cGMP documentation and compliance with SOPs, batch records, and regulatory requirements.

• Collaborate with Quality, Manufacturing, and Technical Operations teams to investigate and resolve quality events and deviations.

• Identify and implement process improvements that enhance efficiency, compliance, and productivity.

• Mentor and train junior team members on manufacturing processes, troubleshooting, and GMP best practices.

• Maintain a strong safety culture and stay current on advancements in gene therapy manufacturing technologies and industry regulations.

Qualifications

• Must have at least a Bachelors or Masters Degree in the field.

• Must have at least 5+ years of experience in pharmaceutical or gene therapy manufacturing environments (if you are just short of 5 years, we may still be open to considering you depending on specific experience).

• Experience in upstream or downstream preferred, but not required.

Job Type & Location

This is a Permanent position based out of Grove City, OH.

Pay and Benefits

The pay range for this position is $37.00 - $38.00/hr.

Individual compensation offered for this position within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, geographic location, internal equity, and other pertinent job-related factors.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: Medical, dental & vision Critical Illness, Accident, and Hospital 401(k) Retirement Plan Pre-tax and Roth post-tax contributions available Life Insurance (Voluntary Life & AD&D for the employee and dependents) Short and long-term disability Health Spending Account (HSA) Transportation benefits Employee Assistance Program Time Off/Leave (PTO, Vacation or Sick Leave)

Workplace Type

This is a fully onsite position in Grove City,OH.

Application Deadline

This position is anticipated to close on Oct 20, 2026.

About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email [email protected] for other accommodation options.

San Francisco Fair Chance Ordinance: Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI): We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.