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Research Scientist 3

Massachusetts Institute of Technology

Cambridge, MAFull-time$82–142K/yrSeen 2w agoSeen in employer's feed 2 days ago

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At a glance

Compensation
$82–142K/yr
Location
Cambridge, MA
Schedule
Full-time
Work Authorization
Visa required • Visa sponsorship

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Requirements

Credentials this posting asks for.

Doctorate

Job overview

The Research Scientist 3 in the Zhang Lab at MIT will develop and optimize proteomic, peptidomic, and immunopeptidomic assays, operate LC‑MS instruments, analyze mass‑spec data, lead projects from concept to execution, collaborate across teams, and mentor junior researchers.

Skills & qualifications

RequiredNice to have

Skills

ProteomicsPeptidomicsMass SpectrometryLC‑MS InstrumentationPEAKSFragPipeDIA‑NNSkylineStatistical MethodsProject ManagementScientific Communication

Qualifications

PhD or Equivalent Training

Full job description

Research Scientist 3

  • Job Number: 26095

  • Functional Area: Research - Scientific

  • Department: McGovern Institute for Brain Research

  • School Area: Office of Provost

  • Pay Range Minimum: $82,000

  • Pay Range Maximum: $142,000

  • Employment Type: Full-Time

  • Employment Category: Exempt

  • Visa Sponsorship Available: Yes

  • Schedule:

  • Pay Grade: No Grade

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Posting Description

RESEARCH SCIENTIST 3, The Zhang Lab - Broad Institute of MIT and Harvard, with expertise in proteomics and peptidomes. This individual will develop and optimize quantitative and qualitative proteomic, peptidomic, and immunopeptidomic assays supporting research in programmable therapeutics and human health. Key responsibilities include preparing biological samples, operating and maintaining LC-MS instruments, troubleshooting workflows, and analyzing mass spectrometry data using platforms such as PEAKS, FragPipe, DIA-NN, and Skyline. The scientist will lead projects from concept through execution, contribute to experimental design and research strategy, collaborate across teams, and mentor junior researchers.

The full job description is available, here: https://www.dropbox.com/scl/fi/lwyc355ourlsakli1a9yb/Proteomics-Research-Scientist.pdf?rlkey=9m3v8qz6ysozfad42lntkcmyu&st=8yyrb9e1&dl=0

Job Requirements

REQUIRED: PhD or equivalent training in proteomics, protein chemistry, molecular biology, analytical chemistry, or a related field; expertise in mass spectrometry-based proteomics or peptidomics; experience developing and optimizing proteomic or peptidomic assays; hands-on experience operating and troubleshooting LC-MS instrumentation; proficiency with PEAKS, FragPipe, DIA-NN, Skyline, or similar software; ability to analyze large datasets and apply appropriate statistical methods; record of scientific productivity through publications, method development, or related contributions; strong experimental design, organization, documentation, and project-management skills; ability to work independently, manage multiple projects, and collaborate effectively; excellent written and verbal communication skills. PREFERRED: Experience with immunopeptidomics and mentoring junior scientists.

9/23/2026

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