
Scientist - In Vivo CAR-T Therapy
Philadelphia, PAJob$120K/yrSeen 5 days agoSeen in employer's feed 5 days ago
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At a glance
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Requirements
Credentials this posting asks for.
Job overview
Legend Biotech seeks a Scientist to advance in vivo CAR-T development and cell and gene therapy programs from early discovery through preclinical development. The role involves designing and executing experimental studies, evaluating product potency, efficacy, and safety, and communicating research findings. The scientist collaborates with research and early development teams to help translate scientific concepts into therapeutic candidates.
Skills & qualifications
Skills
Qualifications
Full job description
Legend Biotech USA, Inc. seeks Scientist - In Vivo CAR-T Therapy in Philadelphia, PA. Design, plan, and execute experimental studies to advance cell and gene therapy platforms and pipeline programs, focusing on in vivo CAR-T development from early discovery through preclinical development. Conduct and analyze in vitro and in vivo studies to evaluate product potency, efficacy, and safety. Develop, optimize, validate, and troubleshoot experimental assays and laboratory methods, including cell line engineering, cell-based functional and cytotoxicity assays, ELISA and PCR-based assays, high-throughput binder screening, and viral vector packaging and titration. Analyze, interpret, and summarize scientific data and maintain experimental records and documentation. Prepare technical reports, summaries, and presentations to communicate research findings, results, and conclusions. Collaborate with research and early development teams to support translation of scientific concepts into therapeutic candidates and advancement of cell and gene therapy programs. Requires PhD in Immunology, Biology, Biochemistry, Chemistry, or a closely related field, plus 2 years of experience in hands-on cell and/or gene therapy research. $119,692/year. Email CV to Attn. E. McShane at [email protected].
How this job compares
Set against the 2,042 open Scientist jobs on Olive Jobs, counted October 30, 2026.
- Pay
- This posting$120K/yr
- Pennsylvania median$117–193K/yr36 salary ranges
- US median$103–160K/yr1,103 salary ranges
This rate, $120K, is 21% below the Pennsylvania median midpoint ($151K) — in the lowest quarter of Scientist salary ranges in Pennsylvania.
- Openings
- Olive Jobs lists 100 open Scientist jobs in Pennsylvania and 2,042 across the US. Under 1% of them nationwide are listed as remote or flexible.
- Hiring the most in Pennsylvania
- J&J Family of Companies15 open
- Merck13 open
- CDM Smith7 open
- Experience
- This posting asks for at least 2 years of experience; Scientist postings that state a minimum ask for 3 years at the median (1,464 postings).
- Education
- This posting asks for a doctorate or professional degree; 407 of the 2,042 open Scientist jobs (20%) ask for a doctorate or professional degree.
Counted across the open, public US postings on Olive Jobs on October 30, 2026. Pay medians are the middle values of the low ends and of the high ends of postings that list both ends of a range in the same cadence (a yearly salary or an hourly rate); a range's midpoint is halfway between its ends. Pay and experience figures resting on fewer than 20 postings are left out.
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