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Scientist. B-Cell Immunology ( 6 Month Contract)

Monte Rosa Therapeutics

Boston, MAContractPosted 1mo agoStill listed 3 days ago

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At a glance

Compensation
No compensation found
Location
Boston, MA
Schedule
Contract
Work Authorization
Not specified

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Job overview

Monte Rosa Therapeutics seeks an energetic, highly motivated B‑Cell Biologist for a six‑month contract in Boston to support development and characterization of novel molecular‑glue degraders for autoimmune and inflammatory diseases as part of the Discovery Immunology team.

Skills & qualifications

RequiredNice to have

Skills

ImmunologyOrganization SkillsELISAFlow CytometryMouse WorkHematologyPurificationFlowJoCell BiologyAutoimmunityWestern BlotGraphPad PrismB CellsAttention to DetailDrug DiscoveryResearchPrimary Immune Cell HandlingMouse Tissue ProcessingMeso Scale DiscoveryAlphaLISASimple Western JessMicrosoft ExcelPowerPointCollaborative AttitudeOrganizational Skills

Qualifications

MS in Immunology or Cell BiologyPhD7+ Years Hands‑on I&I Drug Discovery Experience2-4 Years Pharmaceutical Experience

Full job description

Overview

Monte Rosa Therapeutics is seeking an energetic and highly motivated B-Cell Biologist for a 6 month contract, located in Boston to support the development and characterization of novel molecular glue degraders for the treatment of autoimmune and inflammatory diseases. As part of the Discovery Immunology team, this role will broadly support multiple immunology and inflammation (I&I) projects/programs, both in vitro and ex vivo, from early discovery through lead optimization.

The ideal candidate is an immunologist with a strong technical background in B cell immunology, particularly with primary human and mouse cells/tissues, and a demonstrated ability to move projects/programs forward through collaborative teamwork.

Responsibilities

  • Design, optimize and execute experiments using a variety of primary immune cells and tissues isolated from human, mouse or cynomolgus monkey (including PBMCs, B cells, whole blood, spleen, bone marrow, etc.)

  • Process ex vivo mouse tissue (spleen, bone marrow, lymph node, etc.)

  • Explore and characterize target mechanism of action using immuno-assays: Flow cytometry (spectral a plus), Meso Scale Discovery (MSD)/ELISA/alphaLISA, Western blot, Simple Western (Jess)

  • Maintain timely and detailed notes using electronic lab notebook

  • Communicate findings clearly and concisely to both large and small cross-functional audiences

Qualifications

  • MS in Immunology or Cell Biology with 7+ years of hands-on experience in I&I drug discovery research, preferably in a pharmaceutical setting; or a PhD, with 2 -4 years of pharmaceutical experience

  • Experience handling whole blood, primary immune cells and tissue, including cell purification, stimulation, and analysis

  • Solid understanding of B (and T) cell biology in the context of autoimmunity

  • Experience in protein detection/quantitation methodology (e.g., MSD, ELISA, Western blotting, Jess)

  • Multi-parameter flow cytometry expertise is essential

  • Highly proficient with Microsoft Excel/PowerPoint, GraphPad Prism, and FlowJo

  • Collaborative attitude, strong attention to detail, ability to optimize/master experimental techniques, strong organizational skills

How this job compares

Set against the 2,042 open Scientist jobs on Olive Jobs, counted October 29, 2026.

Pay
  • This postingNot listed
  • Massachusetts median$110–150K/yr147 salary ranges
  • US median$31–38/hr89 hourly ranges
Openings
Olive Jobs lists 199 open Scientist jobs in Massachusetts and 2,042 across the US. Under 1% of them nationwide are listed as remote or flexible.
Hiring the most in Massachusetts
Experience
This posting asks for at least 7 years of experience; Scientist postings that state a minimum ask for 3 years at the median (1,463 postings).
Education
1,213 of the 2,042 open Scientist jobs (59%) ask for a bachelor's degree or higher.

Counted across the open, public US postings on Olive Jobs on October 29, 2026. Pay medians are the middle values of the low ends and of the high ends of postings that list both ends of a range in the same cadence (a yearly salary or an hourly rate); a range's midpoint is halfway between its ends. Pay and experience figures resting on fewer than 20 postings are left out.

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