
Director, Translational Pharmacology
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Job overview
Travere Therapeutics seeks a Director, Translational Pharmacology to support scientific evaluation of business development opportunities in rare diseases. The role assesses therapeutic rationale, disease biology, mechanisms of action, pharmacology data, biomarkers, and development feasibility for external assets and collaborations. The director partners with cross-functional teams and external experts, integrates scientific and development data to inform decisions, and contributes to translational pharmacology activities for internal programs and collaborations.
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Full job description
Department: 106200 Research & Non-Clinical Dev Location: San Diego, USA- Remote Be a part of a global team that is inspired to make a difference in the lives of people living with rare disease. At Travere Therapeutics, we recognize that our exceptional employees are vital to our success. We are a dedicated team focused on meeting the unique needs of rare patients.Our work is rewarding - both professionally and personally - because we are making a difference. We are passionate about what we do. We are seeking talented individuals who will thrive in our collaborative, diverse, fast-paced environment and share in our mission - to identify, develop and deliver life-changing therapies to people living with rare disease. We stick by our values centered on patients, courage, community, and collaboration to pursue our vision of becoming a leading biopharmaceutical company dedicated to the delivery of innovation and hope to patients in the global rare disease community. At Travere Therapeutics, we are in rare for life. We continue to courageously forge new paths as we move toward a common goal of elevating science and service for rare patients*.* Position Summary: Travere Therapeutics is seeking an experienced and strategic scientist to join our Research and Nonclinical Development organization as Director, Translational Pharmacology. This individual will primarily serve as a key scientific contributor to external evaluation of business development opportunities, with a focus on assessing therapeutic rationale, disease biology, mechanism of action, translational strategy, pharmacology data, biomarker approaches, and development feasibility for potential external assets and collaborations focused on the rare disease space. The successful candidate will bring strong expertise in pharmacology, translational science, and disease biology, with experience applying scientific judgment to drug discovery and development decisions. This individual will work closely with Business Development, Clinical Development, Clinical Pharmacology, Regulatory, Medical Affairs, Commercial, and external scientific experts to evaluate new therapeutic opportunities, support diligence activities, and help determine strategic fit with Travere's rare disease portfolio and scientific priorities. This role requires the ability to integrate diverse scientific, nonclinical, clinical, competitive, and translational data sets into clear, balanced assessments that support decision-making. The Director, Translational Pharmacology will also contribute to ongoing translational pharmacology activities for internal programs and external collaborations as needed. Responsibilities: Business Development and Scientific Due Diligence Serve as a preclinical biology lead or key scientific contributor for evaluation of business development opportunities ranging from small-molecule to biologics at all stages of development, including external assets, platform-based technologies and research-based collaborations. Assess scientific rationale, mechanism of action, disease biology, pharmacology and toxicology data, translational relevance and therapeutic safety window, biomarker strategy, and development feasibility for potential opportunities. Review and interpret nonclinical andtranslational data alongside clinical, regulatory, and competitive information to identify strengths, risks, gaps, and key value drivers. Partner with Business Development and cross-functional diligence teams to develop scientific assessment reports, diligence questions, risk summaries, and recommendations. Identify critical experiments, analyses, or expert input needed to reduce scientific uncertainty for potential opportunities. Support evaluation of strategic fit with Travere's port
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