Research Associate/Senior Research Associate, Cell Engineering

An affiliate of Colossal is looking for a talented research associate in cell biology with an interest in the derivation, characterization, and gene editing in non-model mammalian organisms. You will work closely with other lab team members in efforts to innovate on protocols of genome editing, reprogramming and lineage differentiation using cutting edge technologies.

This position is based on-site in Dallas, TX. Relocation assistance is available.

Duties and Responsibilities:

• Derive and characterize stable cell lines from primary tissues

• Microdissection skills for cell line derivations

• Test novel cell culture conditions and delivery methods to optimize gene editing

• Expand clonal cell lines for cryopreservation, genotyping and QC assays

• Work with team members to interrogate targeting, genotyping and QC workflows

• Assist with making edited cell lines that meet quality control criteria for downstream SCNT

• Schedule, analyze and execute experiments to deliver on project milestones

• Attend lab meetings, prepares reports and presentations on the progress of projects

• Demonstrate great organizational skills and excellent laboratory record maintenance

Required Skills and Abilities:

• Experience in primary cell line derivation, culture optimization and cryopreservation

• Experience with electroporation and transfection to maximize gene delivery and viability

• Experience immunostaining cells for flow cytometry and fluorescent microscopy

• Exceptional aseptic technique as antibiotic free cultures are standard

• Organized and comfortable multi-tasking to deliver on concurrent projects on time

• Strong written and oral communication skills, as well as creative problem-solving skills

Preferred Skills and Abilities:

• Experience with high throughput imaging platforms and data analysis

• Experience with automated cell culture systems

• Experience with stem cell culture, such as mouse embryonic stem cells (mESC) or induced pluripotent stem cells (iPSC)

Education and Experience:

• BA/BS/MA/MS in biological sciences, bioengineering, molecular biology, genetics, or any science related field.

What Colossal Offers Full-Time Employees:

• Medical, dental, and vision coverage

• Excellent paid time off and company holidays so you can rest and recharge

• Flexible spending accounts (FSA)

• Company matched 401k retirement plan

• Paid parental leave at 100% salary for up to 12 weeks

• Education reimbursement

• An opportunity to help us return the Earth to a healthier state

The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices.

Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.

Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.

EEO is the Law

Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house.

Colossal is proud to be named a Best Place to Work by BuiltIn for 4 years in a row across multiple categories in 2023, 2024, 2025, and 2026:

• #1 on the 50 Best Startups to Work For in Dallas in 2023!

• 100 Best Midsize Places to Work in Dallas in 2024 & 2025

• 100 Best Places to Work in Dallas, TX (All Size Employers) in 2024, 2025, and 2026.

Built In 2026 Award Lists

Great Place to Work Certification Page

Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.

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