
Postdoctoral Researcher Cell Biology
MILWAUKEE, WIResearchSeen todaySeen in employer's feed today
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Job overview
The lab seeks a highly motivated postdoctoral research fellow to lead studies on astrocytes in spinal muscular atrophy and neural progenitor cell disruption following cytomegalovirus infection. Research uses patient-derived induced pluripotent stem cells, neuronal and glial subtypes, forebrain organoids, imaging, molecular methods, and RNA sequencing. The role includes collaboration, mentoring, scientific writing and presentations, and opportunities to apply for independent funding.
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Full job description
JOB REQUIREMENTS: Summary The lab seeks a highly motivated postdoctoral research fellow to lead studies related to one or more of our exciting research areas including 1) the role of astrocytes in motor neuron pathology in spinal muscular atrophy and 2) mechanisms underlying neural progenitor cell disruption following cytomegalovirus infection. To research these topics, the lab uses a variety of approaches including generating and differentiating patient-derived induced pluripotent stem cells into a variety of neuronal and glial subtypes and forebrain organoids, live cell calcium imaging, microelectrode array, fluorescent microscopy, viral gene delivery for over-expression and knockdown studies both in vitro and in vivo, cell surface proteomics, and RNA sequencing. Translational projects are available and collaboration and communication with clinicians from the major adjacent hospitals regularly occurs. Our team is interactive and has multiple ongoing collaborations with other labs in various departments at MCW and at other institutes. We seek PhDs who are highly motivated, mature, and possess excellent interpersonal skills and writing skills. Opportunities are available for presentations at national and international scientific conferences and for applying for independent funding. Primary Responsibilities Independently design, execute, and analyze complex research procedures using induced pluripotent stem cell-derived neurons, astrocytes, microglia, and forebrain organoids Perform calcium imaging on neurons and astrocytes Bring new molecular and/or physiological methods to the laboratory Develop creative new methodologies for lab procedures, including high content imaging, cell surface proteomics, and RNA seq approaches and analysis Teach and guide technicians, rotating graduate students, rotating medical students, and junior graduate students to perform cellular and molecular analyses and help them efficiently organize and analyze their experiments. Participate in lab meetings with the principal investigator and research staff and evaluate/interpret the validity of data, develop methodologies, and evaluate lab procedures. May oversee the work of laboratory personnel including training and development as well as daily work direction/delegation/prioritizing. Be an engaged lab member that works efficiently in a team setting and is willing to engage in lab and department outings. Independently write first drafts of research proposals and first author manuscripts. Present scientific findings at local, national, and international meetings Apply to competitive independent funding... For full info follow application link. EEO/AA Minorities/Females/Vets/Disability The Medical College of Wisconsin is an affirmative action/equal opportunity employer and does not discriminate in hiring or employment on the basis of age, sex, race, color, religion, national origin, veteran status, disability or sexual orientation. ***** APPLICATION INSTRUCTIONS: Apply Online: ipc.us/t/0E66323DE9EB4404 Qualified females, minorities, and special disabled veterans and other veterans are encouraged to apply.
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