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Scientist II, Developability

BigHat Biosciences

San Mateo, CAFull-time$145–165K/yrPosted 2mo agoVerified open 5 days ago

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At a glance

Compensation
$145–165K/yr
Location
San Mateo, CA
Schedule
Full-time
Work Authorization
US work authorization required

Requirements

Credentials this posting asks for.

Bachelor's degree

Job overview

BigHat Biosciences is hiring a Scientist II, Developability. BigHat Biosciences seeks a hands‑on, bench‑driven Scientist II to lead developability R&D projects, drive assay development, support late‑stage characterization, guide experimental strategy, and collaborate cross‑functionally while analyzing data and communicating findings across the organization.

Key focus areas include Lead developability R&D projects by designing, optimizing, and executing high throughput developability assays, Drive developability assessments across programs with strong data interpretation and organization, and Support late‑stage characterization and IND‑enabling studies including formulation screening and stress testing.

Successful candidates bring PhD In Biochemistry Or Relevant Discipline and 3+ Years Industry Experience. Important skills include Artificial Intelligence, Antibodies, Biochemistry, SEC, HIC, and CE‑SDS. Preferred (not required): Automation, CE-SDS, Project Leadership, and Data Interpretation.

Skills & qualifications

RequiredNice to have

Skills

Artificial IntelligenceAntibodiesBiochemistryAutomationSECHICCE‑SDSDLSDSFELISALC‑MSProtein Structure AnalysisAntibody EngineeringBiophysical CharacterizationAnalytical CharacterizationData AnalysisProtein StructuresProject LeadershipData InterpretationMethod DevelopmentStart‑Up ExperienceProject Lead ExperienceDevelopability AssessmentsHigh Throughput Developability AssaysData OrganizationFormulation ScreeningStress TestingPeptide MappingSimulated Administration StudiesExperimental StrategyAutomate WorkflowsTrain ColleaguesQC FrameworksAdapt WorkflowsScientific InterpretationCommunicationMethod OptimizationTranslating Complex DataDevelopability R&D ProjectsLIMS InfrastructureAnalyze DataInterpret Scientific FindingsPropose Next StepsBroadcast Findings ClearlyBiophysical Characterization of AntibodiesAnalytical Characterization of AntibodiesTranslating Complex Data Into Clear ResultsLearning New TechnologiesOnboarding New TechnologiesWorking in a Dynamic Start-Up EnvironmentProject LeadWorking With AutomationAntibody Developability Assessments

Qualifications

PhD in Biochemistry or Relevant Discipline3+ Years Industry ExperienceDeep Bench Experience

Benefits

Medical Insurance
Dental Insurance
Vision Insurance
401(k) Match
Parental Leave
Paid Time Off

Full job description

The Role: BigHat Biosciences is looking for a hands-on, bench-driven scientist to drive antibody developability assessments that advance our Milliner Platform for AI-designed therapeutics. This is a primarily lab-based role where you'll spend the majority of your time at the bench executing and innovating on our developability workflows.

*At BigHat we believe in titles that commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that r esponsibilities and title would adjust as appropriate.

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