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Director, Antibody Discovery

BigHat Biosciences

San Mateo, CAFull-time$220–250K/yrPosted 2w agoVerified open 5 days ago

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At a glance

Compensation
$220–250K/yr
Location
San Mateo, CA
Schedule
Full-time
Work Authorization
Not specified

Requirements

Credentials this posting asks for.

Doctorate

Job overview

BigHat Biosciences is hiring a Director, Antibody Discovery. BigHat Biosciences seeks an exceptional, highly experienced Director of Antibody Discovery to lead the company’s antibody discovery and display function, shape multi‑year strategy, and manage operational execution for high‑quality antibody identification and maturation across diverse antigen types for internal and partnered programs.

Key focus areas include Lead antibody discovery and display functions, setting scientific, technical, and strategic direction, Oversee routine execution of display‑based selection campaigns to enhance affinity, developability, and function, and Manage and mentor a team of scientists responsible for library design, generation, screening, selection, and early optimization.

Important skills include Drug Development, Mentorship, Antibodies, Yeast Display, Phage Display, and Mammalian Display. Preferred (not required): Biotechnology, Biochemistry, Protein Sciences, and Characterization.

Skills & qualifications

RequiredNice to have

Skills

Drug DevelopmentMentorshipAntibodiesBiotechnologyBiochemistryProtein SciencesCharacterizationAssessmentBiopharmaceuticalsMolecular BiologyYeast DisplayPhage DisplayMammalian DisplaymRNA DisplayAntibody Library DesignAntibody Library ConstructionAntibody ScreeningAntibody Selection AnalysisComputational Protein DesignML-Enabled Protein DesignAntibody Structure-Function KnowledgeBiophysical EvaluationFunctional ScreeningMultispecific Antibodies KnowledgeAntibody Fragments KnowledgeLeadershipStrategic ThinkingCommunicationCollaborationSelf-Motivated

Qualifications

Ph.D. In Molecular Biology, Biochemistry, Protein Engineering or Related Discipline10+ Years Experience in Antibody Discovery and Engineering5+ Years Managerial Experience Leading Scientific TeamsMust Be Willing to Work Onsite 5 Days Per Week

Benefits

Medical Insurance
Dental Insurance
Vision Insurance
Parental Leave
401(k) Match

Full job description

The Role: BigHat is seeking an exceptional and highly experienced individual for a position as Director of Antibody Discovery. This individual will lead the company’s antibody discovery and display function. They will be responsible for conceiving of and leading multi-year team and technology strategy as well as managing routine operational execution for identification and maturation of high-quality antibodies across antigen types for both BigHat and BigHat-partnered therapeutic research programs.

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