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Senior/Research Associate, Functional Genomics

NewLimit

South San Francisco, CAFull-time$75–100K/yrPosted 3mo agoVerified open 5 days ago

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At a glance

Compensation
$75–100K/yr
Location
South San Francisco, CA
Schedule
Full-time
Work Authorization
Not specified

Requirements

Credentials this posting asks for.

Bachelor's degree

Job overview

NewLimit is hiring a Senior/Research Associate, Functional Genomics. NewLimit is a biotechnology company focused on extending human healthspan by reprogramming the epigenome. The Senior/Research Associate will join the Epigenetic Editing group, leveraging functional genomics, pooled perturbation screening, and machine learning to discover therapies that restore cellular function and combat age‑related disease.

Key focus areas include Collaborate with Single Cell Technology team to implement large‑scale single‑cell perturbation experiments with custom chemistries, Build recombinant DNA vectors by synthesis and cloning for large‑scale single‑cell perturbation experiments, and Prepare, titer, and apply lentiviral or AAV viral vectors to transduce mammalian cell lines and primary cells.

Successful candidates bring Bachelor's Degree In Cell Biology, Molecular Biology, Or Related Natural Science Or Industry Experience and 2+ Years Work Experience In Cell Or Molecular Biology Laboratory. Important skills include Molecular Biology, Recombinant DNA Vectors, Viral Vectors, Molecular Cloning, Nucleic Acid Analysis, and RT-qPCR. Preferred (not required): Next-Generation Sequencing Assays, Functional Genomics, FACS, and Flow Cytometry.

Skills & qualifications

RequiredNice to have

Skills

Molecular BiologyRecombinant DNA VectorsViral VectorsMolecular CloningNucleic Acid AnalysisRT-qPCRGel ElectrophoresisMammalian Cell CultureNext-Generation Sequencing AssaysFunctional GenomicsFACSFlow CytometryComputational Skills for Next-Generation Sequencing AnalysisPython ProgrammingUnixSingle Cell Genomics MethodsEpigenetic Reprogramming MethodsCell Fate EngineeringTargeted Epigenetic Editing

Qualifications

Bachelor's Degree in Cell Biology, Molecular Biology, or Related Natural Science or Industry Experience2+ Years Work Experience in Cell or Molecular Biology Laboratory

Benefits

Medical Insurance
Dental Insurance
Vision Insurance
401(k) Match
Parental Leave
Paid Time Off

Full job description

About NewLimit NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.

Position NewLimit is seeking a Senior/Research Associate with experience in molecular biology to join our Epigenetic Editing group. Pooled screening technologies are at the heart of our discovery engine, allowing us to rapidly search for epigenetic reprogramming therapies that restore cell function and reduce the burden of disease.

As a member of our team, you will:

  • Collaborate with our Single Cell Technology team to implement large-scale, single cell perturbation experiments with custom chemistries

  • Build recombinant DNA vectors by synthesis and cloning to enable large-scale single cell perturbation experiments

  • Prepare, titer, and apply viral vectors (lentiviral, AAV) to transduce mammalian cell lines and primary cells

  • Contribute to scaling and improving pooled single cell perturbation screens Requirements

  • Bachelor’s degree in cell biology, molecular biology, or a related natural science or industry experience

  • 2+ years of work experience in a cell or molecular biology laboratory (academic or industry)

  • Experience with molecular cloning, nucleic acid analysis (RT-qPCR, gel electrophoresis), and related molecular biology methods

  • Experience with mammalian cell culture Nice to have

  • Experience with next-generation sequencing assays and functional genomics

  • Experience with FACS or flow cytometry

  • Computational skills for next-generation sequencing analysis (Python programming, Unix)

  • Experience with single cell genomics methods

  • Experience with epigenetic reprogramming methods for cell fate engineering or targeted epigenetic editing Benefits NewLimit offers generous benefits to ensure our team can focus on our mission:

  • Health, dental, and vision insurance

  • 401(k) with company match

  • Paid parental leave

  • Industry-leading paid time off (PTO) — 20 days/year for all employees + holidays

  • Meals and snacks on-site Salary Range: $75,000 to $100,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. NewLimit offers a competitive benefits package, which includes a 401k, healthcare coverage, and 20 days of PTO. Learn more at: https://www.newlimit.com/careers *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future.

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