Sr. Manager, Clinical Operations

About The Role: The Sr. Manager, Clinical Operations reporting to the Director, Business Development and Strategic Partnerships will drive the operational execution and strategic management of high-impact alliances central to 10x Genomics’ effort to advance future diagnostic applications for single cell and spatial technologies.

Key responsibilities for this role include: managing a portfolio of academic collaborations and strategic partnerships according to established milestones and outcomes, leading the operational execution for large-scale, multi-year collaborations with premier academic institutions to generate evidence for future clinical applications of single-cell and spatial technologies, and driving collaboration between internal cross-functional teams and external partners to achieve desired results.

The ideal candidate is an action-oriented and highly-effective leader who has previously managed clinical research studies involving large numbers of patient samples and complex molecular testing or biomarkers.

What You Will Be Doing: Clinical Operations and Study Execution

• Study Execution : Manage the operational execution of large-scale, longitudinal clinical research studies according to established agreements with academic institutions

• Timeline & Risk : Own and drive clinical research study timelines, deliverables, and operational plans ensuring adherence to sampling schedules; identify operational risks regarding enrollment, setup, or logistics early, implementing mitigation strategies to maintain study integrity.

• Sample Logistics & Chain of Custody : Establish and enforce auditable procedures for sample collection, tracking, and chain of custody, ensuring compliant transport from clinical sites to 10x Genomics laboratory.

• Budget & Resource Oversight: Manage the study budgets, including the oversight of reimbursement, equipment provisioning, and consumables provided to partner sites.

• Regulatory & Quality Compliance : Ensure all study activities comply with IRB protocols, patient consent requirements, and GCLP/CLIA standards where applicable.

Academic Collaboration Management

• Portfolio Management: Manage a diverse, high-value portfolio of academic collaborations and strategic partnerships to ensure all projects and agreements track toward established milestones and outcomes.

• Stakeholder Management : Act as the primary liaison between internal teams and key stakeholders at relevant academic institutions and industry partners to foster strong, collaborative relationships that drive engagement and performance.

• Contract Lifecycle Management: Oversee compliance with contractual obligations, milestones, and deliverables, working closely with Legal, Finance, and Business Development to drive contract amendments or renewals as needed.

To Be Successful, You Will Need:

• An Advanced degree (M.S., PharmD, Ph.D., M.B.A.) in a Life Science, Clinical, or related field is required.

• 8+ years of relevant industry experience with 4-5 years of experience in Clinical Operations within the diagnostics, biotechnology, or pharmaceutical industry.

• Direct experience managing research studies involving large numbers of patient samples and complex molecular testing or biomarkers

• Deep understanding of clinical study execution, site management, and the complexities of clinical sample logistics and chain of custody.

• Preferably, experience in managing high-value strategic alliances and driving value through the successful execution of collaborative research, development, or commercialization agreements.

• Demonstrated ability to manage competing priorities, swiftly resolve complex operational problems, and drive tangible results.

Preferred skills and experience

• Thrives in a fast-paced environment with a ‘roll up your sleeves and get it done’ mentality.

• Excellent at communicating, organizing, and leading external stakeholders and internal cross-functional teams to achieve desired outcomes.

• Comfortable leading through ambiguity and change; focusing on finding practical solutions and driving clarity to maintain program momentum.

• Exceptional at building strong, collaborative relationships with diverse stakeholders, including external investigators, and internal technical and executive teams.

• Willing to travel up to 25% for site visits, investigator meetings, and external partner engagement.

• Startup or small biotech experience. Familiarity with CLIA/CAP standards as they relate to samples sent to a centralized testing laboratory is preferred.

Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience. At 10x, base pay is also just one component of the Company’s total compensation package. This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company’s total compensation package.

Pay Range

$173,100—$234,100 USD

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

Please be aware of recruitment scams impersonating 10x Genomics. All recruiting communication will come from email addresses @ 10xgenomics.com . We also want to encourage you to apply to 10x Genomics positions directly on our careers site, Careers.10xgenomics.com or from reputable third party sites, such as LinkedIn or Indeed. We will never request payment or sensitive personal information during the recruiting process.

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