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Research Scientist, Cellular Physiology

Nudge

San Francisco, CAFull-timeNo compensation foundPosted 1y agoVerified open 3 days ago

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At a glance

Compensation
No compensation found
Location
San Francisco, CA
Schedule
Full-time
Work Authorization
Not specified

Requirements

Credentials this posting asks for.

Doctorate

Job overview

Nudge is hiring a Research Scientist, Cellular Physiology. Nudge is developing a non-invasive, ultrasound-based device to stimulate and image the brain at high resolution and depth, aiming to improve people's lives. This vertically integrated effort involves building cutting-edge hardware, software, and research capabilities. The company seeks exceptional individuals who are dedicated to their craft, embrace challenging work, and execute relentlessly with rigor and integrity.

Key focus areas include Develop methods for characterizing the mechanisms of action of ultrasound on neural tissue, Design and execute experiments in vitro to determine the impact of ultrasound on cellular properties, activity, and plasticity, and Explore ultrasound parameter optimization for driving cellular activity and plasticity.

Successful candidates bring PhD Or Postdoc In Neuroscience Or Molecular/Cellular Biology Or Biomedical Engineering Or Similar Engineering Discipline. Important skills include Neuronal Cell Culture, Human IPSC-Derived Neurons, Slice Methods, Advanced Microscopy Techniques, Two-Photon Calcium Imaging, and Electrophysiology.

Skills & qualifications

RequiredNice to have

Skills

Neuronal Cell CultureHuman IPSC-Derived NeuronsSlice MethodsAdvanced Microscopy TechniquesTwo-Photon Calcium ImagingElectrophysiologyNeural Recording TechniquesGenetic ToolsViral TransductionCRISPR-Based ApproachesMolecular Manipulations in Neural TissueTechnical ContributionHigh IntegrityStrong Professional JudgementIndependent ThinkingRelentless Execution Approach

Qualifications

PhD in NeurosciencePhD in Molecular/Cellular BiologyPhD in Biomedical EngineeringPhD in Similar Engineering DisciplinePostdoc in NeurosciencePostdoc in Molecular/Cellular BiologyPostdoc in Biomedical EngineeringPostdoc in Similar Engineering Discipline

Full job description

About Nudge

At Nudge, our mission is to develop the best technology for interfacing with the brain to improve people's lives. We're starting with an approach that we believe can help the most people the fastest, and also allow us to learn as much about the brain as possible: developing a non-invasive, ultrasound-based device that can stimulate and image the brain at high resolution and depth. This is a vertically integrated effort building cutting-edge hardware, software, and research capabilities to create products that can benefit millions — and eventually billions — of people.

To succeed, we need to assemble world-class teams across everything we do. We hire people who are exceptional at their craft, believe hard things are worth doing, and execute relentlessly — people who expect the highest levels of both rigor and integrity from each other.

About the role

As a research scientist focused on cellular physiology at Nudge, you will:

  • Develop methods for characterizing the mechanisms of action of ultrasound on neural tissue

  • Design and execute experiments in vitro to determine the impact of ultrasound on cellular properties, activity, and plasticity

  • Explore ultrasound parameter optimization for driving cellular activity and plasticity

  • Translate in vitro findings to inform human neuromodulation studies

About you

We are looking for research scientists of all levels but regardless of your career level, you should have:

  • A PhD or postdoc in neuroscience, molecular/cellular biology, biomedical engineering or a similar engineering discipline

  • Exceptional proficiency in neuronal cell culture, including human iPSC-derived neurons, and slice methods

  • Experience applying advanced microscopy techniques (e.g., two-photon calcium imaging), electrophysiology, or other neural recording techniques to characterize cellular and synaptic physiology

  • Experience developing or using genetic tools (viral transduction, CRISPR-based approaches, etc.) for molecular manipulations in neural tissue

  • A demonstrated history of exceptional technical contribution

  • High integrity and strong professional judgement

  • A high level of independent thinking and relentless execution approach

You've read the whole posting — now see how you match it.